Biomedical language models (LMs) provide strong representations for clinical tasks, but they often fail to capture the hierarchical structure among medical concepts. This limitation is especially pronounced for rare and fine-grained clinical codes in long-tailed vocabularies, where hierarchy-agnostic LM representations become less informative as concept frequency decreases. We introduce Semantic Medical Identifier (SMI), a training-free framework for constructing ontology-grounded Semantic IDs and hierarchy-aware medical concept representations. For each diagnosis, procedure, or medication concept, SMI defines its Semantic ID as the coarse-to-fine path through an expert-defined medical ontology. SMI then aggregates frozen biomedical LM embeddings across the corresponding ontology levels to form hierarchy-aware medical concept representations that preserve coarse-to-fine clinical semantics. The base SMI uses uniform aggregation across ontology levels, while a level-weighted variant selects global level weights on validation data. Our theoretical analysis shows that SMI yields more informative medical concept representations than hierarchy-agnostic LM embeddings, particularly for rare and fine-grained clinical concepts. Experiments show that SMI captures meaningful hierarchical structure and improves clinical relation prediction. On MIMIC-IV, SMI improves mortality prediction, readmission prediction, drug recommendation, and rare drug prediction. On eICU, SMI yields more robust patient representations under cross-hospital distribution shift.
https://arxiv.org/abs/2610.18672
Recent multimodal large language models (MLLMs) achieve strong results on video question answering, yet often fail to recover the temporal structure that makes a video coherent. They may merge neighboring events, miss single-event progression, or infer implausible relations across events. We study structured temporal understanding as the ability to recover event structure from visual evidence, including event boundaries, single-event progression, and multi-event relations. We argue that this gap arises from a mismatch between current post-training objectives and temporal reasoning, where caption-style supervision allows models to rely on language shortcuts rather than visual temporal grounding. To address this, we propose EventLens, a vision-centric reinforcement learning framework that learns video understanding through event-structure recovery. Instead of reconstructing captions, EventLens trains models to recover temporal structure under controlled perturbations, such as altered temporal granularity, reversed progression, and shuffled event order. We instantiate this framework with a three-level temporal ontology and derive three verifiable task families: event segmentation, progression discrimination, and multi-event relation reasoning. These tasks admit deterministic rewards, enabling task-specialized GRPO training without human preference labels or learned reward models. We further introduce multi-teacher on-policy distillation (MT-OPD) to consolidate specialized policies into a unified model. Experiments on Qwen3-VL backbones show consistent improvements on temporal grounding and event-sensitive reasoning benchmarks, while preserving general video-QA performance. Learning curves further demonstrate that EventLens achieves comparable downstream transfer with significantly reduced training cost compared to direct mixed RL optimization.
https://arxiv.org/abs/2610.16172
Phase-annotated conversational data is essential for studying the progression of online grooming of minors and for developing early warning tools. However, the only publicly available source (i.e., Perverted-Justice archive, which contains a subset coded using ChatCoder) is small, outdated, and frozen. We present a synthetic corpus of groomer-victim exchanges, generated using a retrieval-augmented pipeline running on institutional hardware. This pipeline uses an openly available, eight-billion-parameter, refusal-ablated language model. The corpus was created using the five stages of the responsible-generation protocol for synthetic datasets: ontology-driven design based on the ChatCoder luring-communication scheme (eight communicative tags mapped onto four grooming phases); multi-model prompt testing; human-in-the-loop supervision; semantic and feature-level validation; and modality-aware documentation. The released corpus contains 2,121 unique exchanges across seven tags and four phases, each accompanied by a Plutchik emotion field. Validation quantifies the integrity and lexical profile of the corpus, as well as the reproduction of real seed lines, in-domain label recoverability (tag accuracy: 0.85; phase accuracy: 0.93) and its transfer to real ChatCoder offender lines, which were coded automatically at the eight-tag level (31,640 lines) and by human coders at the three-construct level (10,876 posts). Accuracy was measured for lexical and sentence-embedding features, while a real-versus-synthetic discriminator was able to separate the two domains with 91% accuracy. The scope of the corpus includes controlled, phase-conditioned experimentation, pipeline development and augmentation alongside real data and awareness material. The corpus, its datasheet and the audit code are released with vetted access.
https://arxiv.org/abs/2610.15908
We present Gugak-VocalSet, the first publicly available audio dataset for Korean traditional singing with dense annotations of sigimsae, a structured pitch contour system of vocal expressions. Gugak-VocalSet contains 24.5 hours of unaccompanied solo vocal recordings across 305 tracks of representative repertoire curated by the National Gugak Center, performed by 20 professional singers in a controlled studio environment with fixed key and tempo. In addition to genre, lyrics, and mood/timbre tags, the dataset provides a unified sigimsae ontology and approximately 68,000 segments (71,700 instances including multi-label) of audio-grounded sigimsae annotations; the ontology adopts a functional-position-based hierarchy designed for consistent application across genres, and 14 expert annotators specializing in Korean traditional music performed segment-level labeling accordingly. Baseline experiments on sigimsae classification and event detection show that domain-informed F0 representations remain competitive with, and on classification surpass, frozen probing of a general-purpose music foundation model, while pitch and spectral cues play complementary roles in event-level detection. Companion page: this https URL
https://arxiv.org/abs/2610.15350
LLMs increasingly support sensor-based human activity recognition (HAR) by linking motion signals with activity semantics and physical knowledge. Retrieval-augmented generation (RAG) grounds decisions in sensor examples and domain features, enabling training-free target-user inference with less dependence on raw numerical arrays. However, existing LLM/RAG-based HAR typically searches single-level activity spaces using static population knowledge. Consequently, they compare many unrelated candidates using the same static population evidence and overlook personalized motion patterns. We propose OntoAR-HAR, an ontology-guided agentic RAG framework combining static population and personalized knowledge. Its tree-structured activity ontology decomposes classification into local decisions among semantically related activities. The static store supplies node-constrained examples, while offline-discovered executable signal features provide numerical evidence for local distinctions. During inference, the personalized store collects selected user observations, which the LLM integrates with static knowledge and signal features while traversing the ontology to an activity label. Cross-subject and heterogeneous-sensing experiments show complementary gains from hierarchical retrieval and personalized memory across multiple LLM backbones, achieving state-of-the-art performance. By explicitly modeling hierarchical relations across activity granularities, OntoAR-HAR also addresses the long-overlooked semantic inclusion problem and avoids treating related labels as independent categories.
https://arxiv.org/abs/2610.15292
To evaluate whether a compact bidirectional state-space autoencoder improves joint classification of species, cell type, and disease state from single-nucleus RNA-sequencing profiles in heart failure (HF), while yielding interpretable gene attributions. Building on the dense denoising autoencoder (DAE) and MLP framework of Ruz Jurado et al., we developed scHFBiMamba, combining a bidirectional Mamba autoencoder (BiMambaAE) with an MLP head. BiMambaAE maps 16,545-gene profiles to 350-dimensional latent representations using 13.2M parameters, about 14.6-fold fewer than the dense DAE (192.9M). We compared six encoder-classifier configurations on 38,275 held-out cardiac nuclei using McNemar tests with Benjamini-Hochberg correction, and assessed nine classifiers on frozen representations. Biological relevance was evaluated by comparing SHAP-derived differentially explained genes with differentially expressed genes against curated HF-related Gene Ontology keywords. BiMambaAE+MLP achieved the highest aggregate F1: pooled macro-F1 across 13 outputs was 0.966 versus 0.957 for DAE+MLP, and the mean category macro-F1 was 0.977 versus 0.970. It significantly improved cell-type and disease-state accuracy (adjusted p=7.1e-3 and p=4.8e-6, respectively), with species F1 of 1.000. SHAP-derived differentially explained genes achieved a pathway-enrichment benchmark F1 of 0.105 versus 0.053 for differentially expressed genes. Compact bidirectional state-space autoencoders can outperform substantially larger dense autoencoders for joint cardiac transcriptomic classification while reducing parameters. scHFBiMamba enables accurate multi-task prediction and hypothesis-generating gene-level interpretation. Code: this https URL.
https://arxiv.org/abs/2610.15117
ScienceBuddy-PV adapts the ScienceBuddy recursive-in-recursive design to panvascular intervention research through a structured evidence ledger, device-vessel ontology, abstention contract and retained failure bank. Recursive harness optimization and outer-loop model learning, including reinforcement learning, are specified but not executed. We audit a fixed component, rather than the complete agent system, using separate ARCADE syntax and stenosis tasks (1,000 training, 200 validation and 300 test images per task). A shared task-masked convolutional model was trained once per representation setting; its parameters and the heuristic support gate were then held fixed, with the stenosis threshold selected on validation data. On the locked test sets, syntax Dice was 0.475 (95% CI 0.459-0.490) and stenosis Dice was 0.231 (95% CI 0.214-0.249). Stenosis pixel AUROC was 0.957 and AUPRC was 0.180 at prevalence 0.00975. The gate accepted 76.7% of stenosis-frame outputs versus 100% for a score-only comparator. In a constructed mask audit, it accepted 44.3% of reference candidates and rejected 55.7%, exposing the cost of abstention. Acceptance does not establish correctness or clinical safety. This public-data component audit makes support and abstention measurable and provides a reproducible protocol for future collaborative agent studies. It does not demonstrate recursive improvement, patient-level validity or clinical device recommendations.
https://arxiv.org/abs/2610.14523
Automatic speech recognition produces words but drops the non-verbal content of a recording: the breaths, coughs, sighs and laughter of the speaker, and the horns, music or barking around them. We describe Speech Event Detector, a 5.8-million-parameter convolutional-Transformer model that outputs probabilities every 40 ms for 54 event classes (20 speaker vocalizations and 34 background sounds), together with post-processing that converts these probabilities into timestamped events and a procedure for merging the events into a Whisper transcript. The model is trained on material drawn from seven public datasets whose labels come in incompatible forms: single detected regions, free-text tags with timestamps, temporally strong ontology labels, symbols embedded in transcripts, isolated recordings and environmental recordings. We unify them using rule-based label mapping, recover timestamps for transcript-embedded labels through CTC forced alignment, locating 6,360 of 8,620 sounds, and combine about 168 hours of real annotated training recordings with synthetic mixtures and augmentation using real background noise. Per-class thresholds for two operating profiles are tuned on real held-out recordings, and performance is estimated using two-fold cross-validation. On whole held-out recordings from four datasets, considering the 48 classes with at least ten held-out events, the sensitive profile detects an average of 49 percent of a class's events, covering 67 percent of all 9,367 events, at a macro precision of 0.30. The balanced profile achieves a macro recall of 0.37 at a precision of 0.36, with macro event F1 scores of 0.32 and 0.33, respectively. The detector runs about 39 times faster than real time on eight CPU threads.
https://arxiv.org/abs/2610.14232
This paper details our submission to KnowledgeGraphEval 2026 Subtask 2 on directed Arabic relation extraction. We explored encoder-based and large language model approaches for predicting one of 40 relations or no_relation from an Arabic sentence and a subject-object pair. Our encoder systems use typed entity markers and separate relation-existence and relation-classification heads, while our LLM systems fine-tune Yehia and Qwen3.5 with QLoRA and ontology-constrained prediction. Our best system, an ensemble of Yehia-RE, Qwen-RE, and TypedPair, achieved a micro-F1 score of 94.06 and ranked 1st in Subtask 2. Yehia-RE (full-vocabulary) achieved 92.98, while the best encoder and Qwen-RE achieved 92.69 and 91.94 respectively. Our results highlight the importance of constrained prediction and complementary modeling approaches for Arabic relation extraction.
https://arxiv.org/abs/2610.12742
Event ontology is the foundational framework for defining events in a dataset. Event type induction generally involves domain experts who define guidelines for creating event types and their names based on the dataset's domain and scope. However, this process is resource-intensive in terms of annotation costs and is prone to human biases. To alleviate the need for manual event ontology creation, we propose the CLUE framework for event type induction, naming, and annotation. Our main contributions in this work are: 1) designing a novel joint embedding representation for expressing both the verb-centric view and the semantic view of events; 2) event type induction using contrastive loss guided clustering; 3) event naming and refinement. Experiments demonstrate the effectiveness of our method. Our code is available at this https URL.
https://arxiv.org/abs/2610.12580
Large Language Models (LLMs) have renewed interest in autoformalization. Yet, when First-Order Logic (FOL) is considered as the target formalism, the field still lacks a unified task formulation and a systematic survey. This paper addresses this gap: we first provide a principled definition for the FOL-autoformalization task by distinguishing Ontology Extraction from Logical Translation, showing how their conflation obscures (cross-study) evaluation; we review existing datasets, evaluation metrics, and LLM-based methods, including fine-tuning, prompting, and verification-based refinement; we identify open challenges in benchmarking, semantic evaluation, ontology-aware methods, and end-to-end applications.
https://arxiv.org/abs/2610.12030
Scholarly Knowledge Graphs (SKGs) support literature search, scientific discovery, and agent-assisted research. Yet, most approaches to SKG construction pre-specify the knowledge unit to be represented, typically named scholarly entities or contribution-level statements, and retain only the publication content expressible through that unit. This choice produces two dominant yet distinct paradigms: concept-centric SKGs that preserve entities and local relations, and statement-centric SKGs that capture high-level discourse in sentences. In both cases, the graph reflects a chosen extraction target rather than how a paper constructs and communicates knowledge. We introduce SUDO, the Scholarly Upper Discourse Ontology, which defines how knowledge elements are organized and related to form a paper's research narrative, namely its scholarly discourse. Using linguistic principles that generalize across fields and tasks, SUDO enables each publication's scholarly discourse to be constructed from the bottom up as a coherent, source-grounded representation. Applied consistently across papers, the same structure connects their research narratives into a global scholarly discourse without discarding local context or provenance. We demonstrate SUDO's capabilities across a comprehensive suite of scholarly knowledge-modeling use cases and performance improvements on a downstream Large Language Model (LLM)-based scientific QA task.
https://arxiv.org/abs/2610.33018
Large language model (LLM) agents are beginning to operate industrial energy equipment, and what they get right depends on what they are told about the plant. Established building ontologies name many kinds of points across many sites, whereas an industrial equipment system needs few entities with much knowledge about each. This study proposes the ontology tower, a narrow-and-deep ontology of a single equipment system whose knowledge deepens in two ways: through quantities derived from the measured points by physical relations, and through lessons from the operating journal incorporated as knowledge nodes. On a real low-humidity air-handling test plant operated daily through a programmable logic controller, agents received a text projected from its tower in a preregistered evaluation of nine tasks replayed from the plant's records, using four open-weight models from 9 to about 750 billion parameters. This knowledge raised the rate at which the agents avoided the most plausible misjudgment of each task by about 20 percentage points, and the overall task score of the 9-billion-parameter model as much as that of the largest. Operating lessons were used when incorporated into the tower or placed in the prompt as records, but seldom when left in the journal behind a search tool. In live runs through an invariant safety layer, the agents brought the controlled variable into its target band in 12 of 14 runs. An ontology narrow in entities but deep in what is known about them can thus supply the knowledge that an agent for an industrial equipment system needs.
https://arxiv.org/abs/2610.11768
Large language models (LLMs) offer promising potential for next-visit diagnosis prediction, owing to their ability to integrate longitudinal clinical evidence and reason over it in natural language. However, reinforcement learning for LLM reasoning commonly rewards each trajectory according to the correctness of its final answer. In next-visit diagnosis prediction, multiple diagnoses can be simultaneously valid, but independently rewarding one diagnosis per trajectory does not distinguish repeated hits from coverage of different diagnoses. The policy can therefore concentrate on a few correct diagnoses, leaving others uncovered. Meanwhile, LLM tokenizers can split ICD codes into several generic tokens with limited clinical meaning, requiring multiple decoding steps to predict each diagnosis and hindering reasoning over a large disease vocabulary. To address both challenges, we propose CARing, a framework that represents diagnoses with compositional Semantic IDs (SIDs) and optimizes reasoning trajectories for multi-label coverage. Concretely, we first encode ontology-enriched disease semantics into compact SIDs through residual quantization, and ground the resulting SID tokens in natural language and longitudinal EHR contexts through multi-task alignment and reasoning-enriched training to unlock transferable LLM reasoning. CARing further improves unordered multi-label prediction through a coverage reward for reinforcement learning and multi-positive supervision. At inference time, the model supports both efficient direct constrained decoding and multi-chain reasoning with rank fusion. On MIMIC-III and MIMIC-IV, CARing exceeds all EHR-trained baselines in weighted F1 and attains the highest top-k recall at every reported cutoff, including R@30 of 46.04% and 46.52% in reasoning mode. Our codes and logs are available at this https URL.
https://arxiv.org/abs/2610.10641
Many rare genetic diseases are associated with recognizable craniofacial features. However, traditional approaches for describing facial morphology rely largely on qualitative clinical observation and free-text descriptions, which are often subjective, non-standardized, and difficult to reproduce across observers and institutions. Although the Human Phenotype Ontology (HPO) provides controlled terms for describing facial features, these terms are typically categorical rather than quantitative and may vary depending on examiner experience and interpretation. Here, we present FaceKit, a computational framework for quantitative facial phenotyping from frontal facial photographs. FaceKit extracts standardized measurements of facial landmarks and derived 120 morphological features, then reports feature-level z-scores representing deviation from population reference distributions. The reference distributions are built from the FairFace dataset spanning diverse ancestral groups. We evaluated FaceKit on a curated subset of the GestaltMatcher Database covering 50 rare-disease cohorts. In addition to quantitative facial analysis, FaceKit includes synthetic facial image generation to support rare disease model development and data augmentation. We also performed privacy evaluation to assess whether synthetic images reveal identifiable information from real patient photographs and could compromise patient privacy. Across disease case studies, FaceKit-derived quantitative measurements captured known facial features associated with rare genetic disorders and provided objective support for clinical phenotyping. Together, these results establish FaceKit as a useful tool for quantitative phenotyping, and has the potential to improve rare disease diagnosis, support genotype-phenotype studies, and enable more reproducible clinical characterization across diverse patient populations.
https://arxiv.org/abs/2610.09288
We present BEACON-SP, an ontology-grounded Graph Retrieval-Augmented Generation (GraphRAG) framework for clinician-facing decision support in behavioral health settings such as suicide prevention, where effective assessment requires integrating heterogeneous clinical, behavioral, social, and temporal evidence. BEACON-SP combines patient knowledge graphs with ontology-guided retrieval to support multi-hop reasoning across diagnoses, medications, risk and protective factors, life events, and temporal relationships. The framework is enabled by a comprehensive suicide prevention ontology that integrates the Three-Step Theory, the Integrated Motivational-Volitional Model, and the Suicide Social Determinants of Health Ontology into a unified representation of patient risk factors. We construct ontology-grounded patient knowledge graphs and evaluate BEACON-SP for clinician-facing question answering. Compared with a vector-based retrieval-augmented generation (RAG) baseline on a 1,500-query benchmark spanning 15 clinical categories and 100 patients, BEACON-SP improves completeness, clinical relevance, and evidence grounding under a corrected comparative evaluation protocol, with a small gain on factual accuracy. In paired criterion-level comparisons, GraphRAG is preferred in 76.4% of cases. These results demonstrate the potential of ontology-guided GraphRAG to provide structured, contextualized patient evidence for clinical decision support.
https://arxiv.org/abs/2610.09026
Natural-language access to RDF knowledge graphs is a core Semantic Web ambition. Large language models (LLMs) have advanced Text-to-SPARQL, yet on unfamiliar graphs they often generate valid queries that misrepresent the populated data model. QRAKEN is a training-free, ontology-agnostic neurosymbolic pipeline grounding generation in empirical graph evidence rather than schema expectations. An offline distiller produces TTQL, a compact description of populated multi-hop patterns, conditional frequencies and path-conditioned literal examples, plus a class-property co-occurrence matrix. Online, TTQL guides the LLM, while deterministic syntax, vocabulary and data-model checks provide diagnostics for iterative refinement. On CK25 (First International Text2SPARQL Challenge), under matched-condition recomputation on a QLever snapshot, QRAKEN achieves strict F1 of 0.643 $\pm$ 0.026 with GPT-4.1 mini and 0.652 $\pm$ 0.012 with GPT-5.4: relative gains of 30% and 32% over the strongest recomputed participant, outperforming systems using the same base model family. Ablations identify TTQL patterns as the dominant driver (+0.31 strict F1 over a shape-only baseline); the refinement loop provides a cheap safety net, rejecting triple patterns unsupported by the co-occurrence matrix. Compared with auto-derived SHACL, TTQL yields 64% higher strict F1, supporting the value of empirical patterns beyond schema exposure. With two local 35B 4-bit open-weight models at zero marginal cost, the same pipeline matches the strongest recomputed participant, and TTQL advantages over shape-only and SHACL baselines persist. Results on a single, relatively small benchmark provide an initial empirical signal; monolithic TTQL injection on very open cross-domain graphs remains the main limitation.
https://arxiv.org/abs/2610.08095
LLM tool-use agents operate in dynamic environments where many actions carry operational risk. However, most safety mechanisms react only after errors manifest. Existing pre-emptive approaches either fine-tune the agent on chain-of-thought deliberation or compile natural-language guardrails into runtime checks, but they do so without exposing a structural, auditable verdict. We propose POLAR, a guardrail framework for small tool-calling agents that assesses reversibility through a structured two-layer ontology. POLAR assigns each action a graded reversibility score by deriving a candidate inverse sequence; calls failing a threshold are pruned before execution. Evaluated on $\tau^2$-bench across six agent models, POLAR improves mean task reward by 0.11 to 0.18 points on airline for four of six agents, but only eight of eighteen model--domain cells improve overall; retail and stronger agents often regress. POLAR provides an auditable structural check and characterizes its task-utility trade-offs. Reward is not a direct measure of prevented harm.
https://arxiv.org/abs/2610.08082
As LLMs increasingly assist in moral reasoning, omission bias, the tendency to prefer inaction even when equivalent framings reverse substantive outcomes, poses a significant risk of skewed decision-making. Yet omission bias remains underexplored in LLM evaluation, with the few existing studies limited in scale and focused largely on utilitarian-deontological conflicts. To address this gap, we introduce OMIT, a benchmark consisting of 218 paired-frame scenarios across 10 conflict types, constructed by leveraging disagreement patterns from an LLM-based, five-perspective philosophical persona panel (utilitarianism, deontology, virtue ethics, care ethics, and contractualism). Evaluating eight LLMs, we find that omission bias is pervasive but inversely correlates with model size within families. We further evaluate four inference-time interventions and find that interventions encouraging models to consider moral principles before committing to a yes/no answer reduce omission bias and increase frame-consistent responses, although lower omission bias rates can also coincide with shifts toward action-biased responses. Ultimately, this work contributes not only the OMIT benchmark, but also a methodology for using diverse philosophical disagreement signals to evaluate framing-sensitive inaction preferences and the distributional effects of mitigation attempts in LLMs under complex moral conflicts.
https://arxiv.org/abs/2610.07847
AI agents are entering production in increasingly consequential environments without a shared semantic standard for what their evaluations actually mean. Scores, traces, judge outputs, and multi juror findings are increasingly used to justify readiness and release decisions, yet they often do not specify what evidence supports a claim, what that evidence can establish, or how the claim leads to a decision. We introduce EIO-Agents, an open specification for interoperable AI agent evaluation built on two layers. The Evaluation Intelligence Ontology (EIO) provides the semantic layer through typed evidence, versioned behavioral predicates, evidence contracts, claims, witness rules, proof status, recurrence, and computable derivations for metrics, findings, controls, and PASS, REVIEW, or BLOCK decisions. The Portable Evaluation Record (PER) provides the system of record: a canonical, content addressed representation of one evaluation that preserves the evidence to decision chain and can be re derived, explained, and verified. Scores summarize, juries interpret, and traces record, but none of them define what the evidence means or what it can prove. EIO provides that missing semantic contract, while PER preserves the resulting evaluation as a portable and verifiable system of record. As AI agents assume greater operational responsibility, evaluation must become more than a collection of scores and verdicts; it must become an accountable artifact whose meaning, evidence, limitations, and decisions can be independently checked.
https://arxiv.org/abs/2610.07675