Accurate localization of abnormalities in three-dimensional (3D) CT scans is essential for linking automated predictions with clinically relevant pathological findings. We propose Uni-Loc, a vision-language framework that unifies pathology classification and 3D localization using scan-level supervision. Uni-Loc derives both predictions and localization maps from spatial similarities between pathology-conditioned queries and image features. A token-to-voxel upsampling module enables high-resolution localization, while gradient-guided thresholding identifies pathology regions without additional learned parameters. Evaluated on five localization tasks comprising 355 annotated CT scans, Uni-Loc achieves macro-averaged voxel-level AUROC/AUPR of 96.1\%/34.5\%, outperforming relevance propagation (80.7%/13.9%) and gradient saliency (88.7%/8.1%). Uni-Loc also achieves classification AUROC of 88.39% on CT-RATE and 78.03% on RAD-ChestCT, improving over a matched baseline. These results demonstrate effective 3D pathology localization without requiring pathology-specific voxel-level supervision.
https://arxiv.org/abs/2611.13330
The task of weakly supervised video anomaly detection is challenging. Existing approaches mainly model video frame features and determine whether anomalies are present based on their magnitudes. In this work, we propose a novel method that incorporates external knowledge into training to improve model performance, robustness, and generalization. We leverage textual prompts and a large language model (LLM) to establish prior information for the specific task, and employ dictionary learning to normalize and compress this information. Moreover, during experiments, we observed inconsistencies in the textual descriptions extracted from similar video frames by image caption models. To address this, we devise a method that leverages an LLM and auxiliary information to ensure consistency in the textual descriptions of similar frames within a video. Finally, we introduce a feature processing approach that incorporates prior knowledge and cross-modal attention mechanisms. This approach learns the relationships and characteristics among different modalities to construct more accurate and reliable feature representations, thereby improving the accuracy and stability of downstream tasks. Experimental results demonstrate that our method surpasses other state-of-the-art approaches.
https://arxiv.org/abs/2611.09536
We introduce SM4RT, a multi-task cascade feed-forward model for dynamic scene reconstruction from RGB videos. While existing feed-forward approaches typically address geometry reconstruction and motion estimation separately--and often predict motions in a single coordinate frame that must account for camera movement--SM4RT solves these tasks sequentially by first reconstructing 3D geometry and then bootstrapping motion estimation from the predicted structure. By expressing each pixel's 3D motion in its corresponding camera frame, SM4RT reduces ambiguity arising from camera motion. To address the sparsity of real-world motion labels, SM4RT further incorporates a weakly supervised loss that regularizes unlabeled point motions using labeled point positions at the other time step. We evaluate motion estimation on three dynamic-scene datasets--Kubric, Waymo, and Point Odyssey--and SM4RT achieves the best performance on most metrics compared with prior baselines. We additionally benchmark geometry reconstruction on five dynamic scene datasets and show that SM4RT achieves competitive performance with state-of-the-art methods. Overall, our unified framework demonstrates that combining geometry reconstruction and motion estimation in a cascade not only avoids performance trade-offs but also enhances motion estimation through improved geometric reasoning.
https://arxiv.org/abs/2611.08436
Geospatial foundation models (GFMs) are reshaping remote sensing by shifting the field from task-specific modeling toward general-purpose geospatial intelligence. Mapping the damage to buildings stands to benefit substantially from this shift, as GFMs pretrained on large-scale Earth observation data provide generalizable geospatial representations that can facilitate effective responses to sudden-onset disasters. Although parameter-efficient fine-tuning (PEFT) facilitates GFM adaptation, parameter efficiency does not necessarily translate into label efficiency. Building damage mapping remains challenging due to scarce pre-existing labeled data or limited time for annotation. When weak supervision is introduced to alleviate the labeling bottleneck, we identify the difficulty of learning sufficiently discriminative representations as a key challenge for label-efficient GFM adaptation. To address this challenge, we propose a Positive-Unlabeled GFM Adaptation (PUMA) framework that requires annotations for only a small number of damaged buildings. More specifically, PUMA integrates non-contrastive weakly supervised representation refinement to mitigate the impact of noisy supervision on representation learning from a gradient perspective, and latent-state-based label disambiguation to enable reversible supervision refinement without requiring class prior estimation. Extensive experiments on disaster benchmark datasets from around the world demonstrated the effectiveness and robustness of PUMA. A real-world application to the 2025 Los Angeles wildfires further highlighted its potential to accurately map damage under highly limited supervision. More broadly, these findings suggest that weakly supervised PEFT offers a label-efficient pathway from GFMs to real-world applications.
https://arxiv.org/abs/2611.08561
Mental-health risks such as depression, dementia, and suicidal ideation can emerge during hospitalization among chronically ill patients and may worsen without timely recognition and intervention. However, most existing mental health studies focus on patients with established psychiatric conditions rather than patients hospitalized primarily for physical illness. In this work, we investigate whether latent mental-health risk in chronically ill patients can be inferred from longitudinal clinical narratives. We construct a weakly supervised cohort around 4,000 patients from MIMIC-III using mental-health evidence extracted from discharge summaries. A hierarchical state-space framework derives mental-health representations from day-wise clinical narratives and models their temporal evolution for risk estimation throughout hospitalization. Preliminary results demonstrate improved binary risk prediction using the proposed representations and show distinct model derived risk trajectories between risk and no-risk cohorts, providing a foundation for studying emerging mental-health risks in chronically ill patients.
https://arxiv.org/abs/2610.35761
Spatial localization of surgical instruments through bounding-box annotations is a foundational component of surgical scene understanding, supporting detection, tracking, interaction analysis, and grounded vision-language applications. Yet existing annotations often cover selected frames, video subsets, or dataset variants rather than complete procedures. Manual extension is time-consuming and expert-dependent. Additionally, weakly supervised and detector-based pseudo-labels require task-specific training and may be imprecise. In this study, we design a scalable MLLM-based annotation framework that converts surgical frames and existing instrument-presence labels into accurate bounding boxes, and systematically analyze its reliability, cost, and design sensitivity. We instantiate the framework using six MLLMs and a multi-call configuration on laparoscopic cholecystectomy in Cholec80. Using a carefully designed stratification scheme, two annotators independently label 1,000 frames, and an expert surgeon reviews one annotation set to establish the reference. Results show that instrument-set F1 ranges from 88.2 to 92.7,whereas mIoU ranges from 0.180 to 0.735, showing that comparable recognition can conceal large localization differences. A structured multi-stage annotation pipeline achieves 0.784 mIoU, compared with 0.735 for the best single-call baseline and 0.814 human-human agreement. Using the best accuracy pipeline, we create and publicly release a spatial extension of Cholec80 comprising 285,977 bounding boxes across all 184,498 annotated frames from the 80 videos. The annotations and human references are made available on GitHub
https://arxiv.org/abs/2610.34218
Surgical scene understanding is a prerequisite for context-aware and intelligent systems in the operating room. Current methods rely mostly on visual data, while acoustic sensing has shown potential to provide complementary information on surgical activity. First approaches for the localisation of surgical activity relied on microphone arrays and acoustic beamforming. This work investigates whether the active instrument can be localized from a single microphone and a camera by learning the correspondence between the appearance and the sound of surgical instruments, without annotating its position. We adapt weakly supervised audio-visual localisation, which learns from the co-occurrence of image and sound, to the surgical setting. We record simulated surgical actions, sawing, drilling, and chiseling, and train the model on these recordings without any spatial annotation to produce a heatmap over the sounding tool. We extend the training objective by two terms: a silence term, which suppresses the output for silence and background noise, and a composite term, which trains the model to select the sounding one of two visible instruments. The model localizes the active instrument on an independent corpus recorded with a different camera and microphone, in which instrument positions were obtained by optical tracking. It separates tool activity from silence and background noise and can attribute sound correctly when two tools are present. Audio-visual correspondence learned from in-domain recordings connects the sound of a surgical action to the instrument that produces it, using a single microphone and a camera. This proof of concept introduces a novel paradigm that enables the detection and localisation of surgical activity without manual annotations.
https://arxiv.org/abs/2610.32816
Developing robust vision models requires large amounts of annotated data, especially for tasks involving fine-grained class distinctions under variable environmental conditions. Even in domains with numerous existing datasets, differences in annotation formats, label definitions and targeted learning tasks hinder data reuse and integration. To address this challenge, we introduce ReLEAP, a scalable Python framework for unifying heterogeneous image datasets through data-source abstraction, systematic reuse of annotations across learning tasks, and mapping of labels to a shared hierarchical taxonomy. We demonstrate its applicability in precision agriculture by integrating fifteen diverse datasets covering a broad range of plant species and annotation types. Beyond unification, ReLEAP enables systematic recycling of existing data and provides a robust foundation for learning-based annotation upcycling. Leveraging this foundation, we conduct extensive cross-dataset and fine-tuning experiments to investigate how domain-specific models trained on unified data and foundation models can be used to automatically generate higher-level annotations under unsupervised, weakly supervised and semi-supervised settings, and how dataset characteristics influence their effectiveness. Our results show that unified data access and annotation upcycling substantially expand the pool of reusable training data and annotations while improving data transparency, enabling more sustainable and resource-efficient use of existing datasets. We release the framework and trained models for academic use to support accessible and collaborative research, particularly in data-scarce and heterogeneous domains.
https://arxiv.org/abs/2610.32289
The performance of medical image segmentation depends on a large amount of annotated data, and most segmentation models experience a significant drop in performance in low-sample-size scenarios. Existing semi-supervised and weakly supervised methods rely on specific network architectures, while traditional multi-view-assisted segmentation methods require strictly paired samples, which limits their clinical applications. To address these issues, we propose DPIF, a general-purpose plug-and-play dual-path interaction framework compatible with arbitrary encoder-decoder segmentation networks, which leverages cross-view anatomical complementarity to reduce annotation reliance. DPIF first performs Sinkhorn optimal transport-based cross-view distribution alignment to establish global semantic correspondence without sample-level pairing. It then adopts conditional mutual information-guided feature decoupling to enable bidirectional knowledge transfer only within the shared semantic space, suppressing view-specific noise. Finally, persistent homology-based topological regularization encodes anatomical invariants as unsupervised priors to mitigate overfitting. Experiments were conducted using 24 baseline models on a private multicenter echocardiography dataset and two public datasets. The results show that DPIF-enhanced models outperform single-view baseline models when trained on comparable amounts of data. Notably, most dual-path variants trained on 40\% - 60\% of the data achieve performance comparable to that of single-view models trained on the full dataset. This demonstrates that DPIF provides a general-purpose and scalable solution for data-scarce multi-view medical image segmentation problems.
https://arxiv.org/abs/2610.31065
Understanding the properties of fish populations is increasingly important. Analyzing fish length, width, and mass is integral to maintaining healthy stock in the aquaculture industry, while counting wild fish populations supports marine conservation and coastal reef restoration efforts. Deep learning-based segmentation models offer a promising means of obtaining such information at scale. Most of these models, however, require costly and time-consuming per-pixel segmentation labels for training, which can take up to two minutes per fish to annotate manually. To address this inefficiency, we propose a weakly supervised segmentation pipeline that requires only point-labeled data (one click per fish) to produce accurate segmentation masks. Our pipeline consists of four stages. First, a point-supervised tracker predicts point annotations for each frame. These points are then converted into motion-informed language expressions, which guide a language-conditioned segmentation model (LMPM++) to capture temporal consistency and produce candidate segmentation masks. Finally, optical flow and background subtraction are applied as post-processing filters to suppress noise from incorrect segmentations. Experiments on the DeepFish dataset show improvement in foreground mean intersection over union (mIoU) as compared to baseline models.
https://arxiv.org/abs/2610.29047
Weak bag-level labels are widely available in computational pathology, whereas reliable instance-level annotations for whole-slide images remain expensive and ambiguous. Weakly supervised multiple instance learning (MIL) achieves strong bag-level classification, but instance-level supervision from attention scores, model predictions, negative bags, or spatial refinement may fail to identify class-specific local evidence. We propose ProtoPur, a prototype-purity pseudo-labeling method for weakly supervised instance-level learning in pathology whole-slide images. ProtoPur estimates class-balanced local purity over prototype regions constructed from frozen foundation-model features, and assigns pseudo-labels to high-purity regions strongly associated with a target class. This purity-first design separates class-specific evidence from negative or shared morphology, with coverage used only to ensure sufficient pseudo-label assignment. We provide a PAC-style analysis showing that the risk of an instance classifier trained with ProtoPur pseudo-labels can be decomposed into a standard uniform-convergence term and a ProtoPur-specific pseudo-label noise term, comprising selected-region mismatch and a coverage residual. Experiments on three public whole-slide image datasets with two pathology foundation encoders show that ProtoPur consistently improves instance-level performance across multiple MIL backbones while maintaining competitive bag-level performance. Pseudo-label quality comparisons on two public datasets further demonstrate that prototype-purity selection provides stronger instance supervision. These results suggest that the foundation-model features contain exploitable instance-level supervision signals, and ProtoPur is a way to reveal and use these signals from weak bag labels without requiring dense instance annotations.
https://arxiv.org/abs/2610.15669
Background: Five-year survival prediction from hematoxylin-and-eosin whole-slide images could support risk stratification, but the task is weakly supervised, and the tissue morphologies carrying prognostic information remain incompletely characterized. Methods: We conducted a retrospective secondary analysis using TCGA-COAD/READ (n=562) for morphology-specific analysis, Alliance/ CALGB 89803 (n=424) for model development, and SurGen (n=218) for external evaluation. We propose MorphContrast, a morphology-aware contrastive multiple-instance learning framework that uses tissue labels as structural supervision for five-year survival prediction. MorphContrast combines gated-attention pooling with three auxiliary objectives: patch-level morphology labels define within-patient contrasts, outcome concordance or discordance defines cross-patient contrasts within matched morphologies, and diversity regularization discourages representational collapse. Morphology-matched patches from patients with discordant outcomes serve as hard negatives, encouraging prognostic discrimination within comparable histologic contexts. Results: Morphology-specific models show weak but distributed prognostic discrimination: adipose tissue achieves an area under the receiver operating characteristic curve (AUC) of 0.622, stroma achieves 0.604, and both perform comparably to tumor epithelium (0.601-0.605). On Alliance/CALGB 89803, the single model achieves an AUC of 0.642, while the post hoc ensemble reaches a pooled out-of-fold AUC of 0.70 and a risk-group hazard ratio of 3.79 (95% confidence interval: 2.55-5.63). On the external SurGen colon cancer cohort (n=218), the single model and ensemble achieve AUCs of 0.669 and 0.678, respectively. Conclusions: These findings support tissue morphology as structural supervision for outcome-aware representation learning in colorectal cancer prognosis.
https://arxiv.org/abs/2610.17603
Respiratory auscultation provides a low-cost means of assessing pulmonary function, yet transient crackles and sustained wheezes can be difficult to recognize in noisy clinical recordings. Conventional deep learning classifiers often operate as black boxes, offering limited insight into the temporal acoustic evidence supporting their predictions. We present RespFocus, a weakly supervised framework that uses multiple instance learning (MIL) to learn inspectable temporal evidence from cycle-level labels and integrate it into classification. We also introduce PedResp2026, a multicenter pediatric respiratory sound cohort collected in routine clinical environments with adjudicated cycle-level annotations. In classification experiments, RespFocus achieves four-class Scores of 69.55\% on public ICBHI 2017 and 72.91\% on PedResp2026. Evidence diagnostics and matched temporal interventions support the functional contribution of the learned evidence to model predictions. Together, these findings highlight RespFocus's potential as a tool for automated respiratory sound diagnosis.
https://arxiv.org/abs/2610.15702
Despite remarkable progress in language understanding and generation, decoder language models continue to exhibit striking failures on numerical data. Numerical examples are typically serialized as text by concatenating feature names with their values (e.g., fat:3.4), while conventional task adaptation applies loss only to the downstream prediction target. This leaves two structures weakly supervised: within-value sensitivity, where digit position determines numerical magnitude, because token cross-entropy contains no explicit numerical metric; and across-field structure, where measurements in the same record are statistically dependent, because target-only tuning provides no direct loss on the measurements or their dependencies. We introduce MoMaTune (Model, Match, then Tune), a two-stage post-training strategy organized around these supervision gaps. Stage 1 applies Model, ordinary next-token prediction densely over label-free serialized records, and optionally adds Match, a same-record consistency objective that aligns representations of different partial views of the same example. Stage 2 applies Tune, supervised fine-tuning for downstream target prediction. We evaluate MoMaTune on 169,285 records from eight public datasets, with 339 of 340 input fields numerical. At 1.5B parameters, Model raises the eight-dataset masked-value imputation aggregate from 0.106 to 0.401, while the three-dataset correct-context gain rises from 0.058 to 0.167. On diagnostics, Model also increases sensitivity to numerically consequential digit changes, while Match improves robustness to informative partial views. Adding Tune yields higher target-supervised embedding aggregates for each tested Stage-1 parent, and the two-stage recipes obtain higher aggregate scores than Tune alone. The same pattern is observed at 4B, 9.6B, and 27B parameters when model embeddings are used for downstream prediction.
https://arxiv.org/abs/2610.15235
Individual animal re-identification from camera-trap imagery is an instance retrieval problem central to non-invasive wildlife monitoring: a query image must retrieve the correct individual from a reference set of known animals. This requires computer vision models to recognize distinctive local patterns in fur, skin, or other visual markings. Current approaches either learn global embeddings as a classification problem, requiring many labeled images per individual while largely ignoring local evidence, or apply off-the-shelf, domain-agnostic image matchers. Although such matchers are pretrained on large and diverse image collections, adapting them to wildlife imagery is challenging because available datasets are small and lack correspondence-level annotations. We study weakly supervised adaptation of a pretrained keypoint matcher using only identity labels, without keypoint-level or geometric correspondence ground truth. We mine informative image pairs with the pretrained matcher, derive weak positive and negative supervision from identity agreement, and contrastively fine-tune the matching network to strengthen correspondences for same-identity pairs and suppress them for different identities. Across open-source wildlife re-identification datasets, our approach improves accuracy over off-the-shelf matchers and a state-of-the-art local--global fusion method. Under an open-world protocol with held-out individuals, it learns a transferable correspondence prior rather than memorizing training identities. To our knowledge, this is the first study of matcher-level, identity-supervised adaptation for animal re-identification. Our method enables data-efficient specialization of image matching models to wildlife domains using identity annotations already available in typical monitoring datasets.
https://arxiv.org/abs/2610.07384
Joint molecular phenotype prediction is complicated by small joint-positive populations and overlapping histological features across alternative molecular states. Existing computational pathology approaches typically predict biomarkers independently or formulate the joint-positive phenotype as a binary endpoint. Independent prediction does not model interactions between biomarker-specific histological representations, whereas binary joint prediction collapses the double-negative and two single-positive configurations into a single negative class. We propose State-Aware Interaction MIL, a weakly supervised method that preserves biomarker-specific histological representations, models their interaction, and supervises the complete four-state molecular configuration. We evaluate the proposed approach for joint BRAF+/MSI+ prediction in colorectal cancer and EGFR+/TP53+ prediction in lung adenocarcinoma using frozen UNI2-h and CONCH pathology foundation-model representations. With UNI2-h, State-Aware Interaction MIL achieved an average precision of 0.5566 in colorectal cancer (joint-positive prevalence 6.8%) compared with 0.5161 for NaiveMTL, and 0.2784 in lung adenocarcinoma (joint-positive prevalence 8.6%) compared with 0.2525 for IndependentPair. With CONCH, State-Aware achieved an average precision of 0.4410 compared with 0.3932 for DirectJoint in colorectal cancer and 0.1659 compared with 0.1226 for DirectJoint in lung adenocarcinoma. These results indicate that pathology foundation-model representations contain predictive information for rare joint molecular phenotypes and that preserving biomarker-specific representations within a structured molecular-state formulation can improve prediction of these phenotypes from histopathology.
https://arxiv.org/abs/2610.06991
The development of Financial Natural Language Processing (NLP) systems for Brazilian Portuguese is hindered by the scarcity of domain-specific datasets. To address this, we present a large-scale corpus of approximately 160,000 Brazilian Portuguese financial news articles collected from web sources. To establish initial benchmarks for a weakly supervised multi-class classification approach based on semantic similarity, we annotated subsets of this corpus both manually and using a Large Language Model (LLM). We evaluated three similarity-based methods -- cosine similarity, K-Nearest Neighbors (KNN), and FAISS-based nearest-neighbor search -- using multilingual semantic embeddings. Our experiments reveal that the task is highly sensitive to label quality and class distribution. On the manually labeled subset, KNN achieved the best performance (47.3% accuracy, 31.9% F1-score), closely followed by FAISS. Conversely, on the LLM-annotated subset, while accuracy reached approximately 50%, F1-scores dropped to near 20%, highlighting the negative impact of label imbalance and noisy weak annotations. These findings establish foundational baselines for a challenging task, underscoring the critical need for high-quality manual annotations. Ultimately, this dataset and our preliminary results provide a reference point for future research in Brazilian Portuguese Financial NLP.
https://arxiv.org/abs/2610.20630
Localizing AI-edited regions is essential for interpretable forensic analysis, but remains challenging due to subtle and spatially distributed artifacts that are misaligned with semantic or object boundaries. Existing approaches rely on pixel-level supervision from controlled editing pipelines, which is difficult to scale and can introduce misleading signals: artifacts frequently extend beyond annotated regions, while out-of-mask pixels are treated as authentic. This limits models' ability to capture transferable evidence and generalize across generators and datasets. To address these issues, we propose ReGFLoW, a Reconstruction-Guided Fake Localization framework under Weak supervision, which is the first weakly supervised approach for diffusion-edited fake region localization. ReGFLoW requires only real/fake labels at the image-level and uses diffusion reconstruction errors as dense spatial guidance to inject them into both feature and score spaces. Furthermore, by artifact-centric multiple instance learning, ReGFLoW utilizes localized diffusion evidence without relying on semantic-affinity or boundary-based pseudo-mask priors. Extensive experiments demonstrate that ReGFLoW achieves stronger out-of-domain generalization than fully supervised learning baselines.
https://arxiv.org/abs/2609.36882
Spatio-Temporal Video Grounding (STVG) aims to localize the spatio-temporal tube in a video corresponding to a natural language query. While recent methods achieve strong performance in fully supervised, weakly supervised, and zero-shot settings, they typically rely on computationally expensive architectures, complex training pipelines, or multimodal large language models. We present Pocket-STVG (P-STVG), a lightweight cascade architecture that addresses STVG by combining efficient pre-trained components instead of large end-to-end models. P-STVG integrates a temporal-aware video encoder based on MobileViCLIP, a spatial encoder-decoder derived from MDETR, and a shared aligned text encoder. Temporal localization is performed through either a lightweight 1D U-Net or a simple thresholding strategy, enabling the same framework to operate in both weakly supervised and zero-shot settings. Furthermore, video representations are precomputed independently of the query, yielding an indexing-friendly pipeline for efficient inference and large-scale video collections. Despite requiring fewer than 90M parameters, P-STVG performs on par with weakly supervised methods and improves on earlier zero-shot approaches at a fraction of their memory and computational cost, establishing a favorable performance-efficiency trade-off for STVG.
https://arxiv.org/abs/2609.31135
Online handwriting provides a non-invasive and low-cost behavioral biomarker for Alzheimer's disease (AD) detection, as it reflects both cognitive planning and fine motor control. Existing handwriting-based AD detection methods usually rely on global trajectory features or whole-sample representations, which can be strongly affected by individual writing style, task-specific variation, and acquisition noise. In this paper, we propose NormPaST-Risk, a healthy-normative Paper-Air selective trajectory state-space risk network for interpretable AD detection from online handwriting. Instead of treating the entire trajectory as a single holistic representation, our method reformulates AD handwriting detection as local disease-relevant segment discovery. Specifically, a multi-scale temporal encoder captures stroke dynamics at different temporal resolutions, while a selective Paper-Air state-space encoder models long-range handwriting progression and distinguishes on-paper motor execution from in-air planning and transition behaviors. To explicitly characterize abnormal deviations, a healthy normative branch learns normal handwriting dynamics from healthy controls, and a task-aware multi-expert segment-risk module estimates segment-level AD risk calibrated by hidden-state changes and normative deviations. A weakly supervised segment-level objective further enables high-risk segment discovery without manual segment annotations. Experiments on the DARWIN benchmark demonstrate that the proposed framework achieves superior AD/HC classification performance compared with existing methods. Moreover, the discovered high-risk segments can be projected back to the original handwriting trajectory, providing interpretable evidence associated with AD-related handwriting variations.
https://arxiv.org/abs/2609.29384