arXiv_AI
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Transparency Disclosures for Chain-of-Thought Monitorability
Abstract
Chain-of-thought (CoT) monitoring is one of the most valuable tools for monitoring advanced AI systems, but it is under threat. We argue that frontier AI developers should report specific indicators to make these threats trackable and to better facilitate coordination to preserve CoT monitorability. We identify five indicators that are both highly relevant and reasonably feasible to disclose, one for each link in a five-step chain on which CoT monitoring depends. The first, third-party CoT access and base architecture specifications, also underpins external verification of the rest. The others span CoT quality (naturalness and faithfulness) and monitoring effectiveness (detection and uplift). An audit of current disclosures by Anthropic, OpenAI, and Google DeepMind shows that no developer covers the full set, but that every indicator has been reported by at least one frontier developer. Because current disclosures rely largely on developers' own evaluations, we also recommend that a cross-developer audit be repeated with deeper access than public disclosures allow, either by embedded evaluators working within developers or by an Independent Verification Organization.
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URL
https://arxiv.org/abs/2611.13873
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Mechanistic Interpretability of Deep Neural Networks: Methods, Frameworks, and Perspectives
2026-11-10 10:29:14Lorenzo Cirillo, Irene Amerini, Andrea CavallaroAbstract
Deep neural networks underpin fundamental tasks in a wide range of signal domains, such as image, audio, and language processing. However, their internal mechanisms are notably difficult to interpret. Internal activations are structured signals transformed across layers that may encode a multitude of interdependent relationships, as individual neurons frequently represent multiple underlying concepts. Mechanistic interpretability aims to uncover the internal mechanisms of neural networks by identifying components whose activations are causally responsible for specific behaviors. In such a context, this article provides an overview of advances in mechanistic interpretability for the analysis of causal inference in deep neural networks.
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URL
https://arxiv.org/abs/2611.13868
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Taxonomy-Agnostic Neurosymbolic Grounding of Robot Kinematics
2026-11-10 10:11:30Bastien Dussard (LAAS-RIS, LAAS), Aur{\'e}lie Clodic (LAAS-IDEA, LAAS-RIS, LAAS), Guillaume Sarthou (LAAS-RIS, EPE UT, LAAS)Abstract
While symbolic reasoning for task allocation requires grounding a robot's physical capabilities, standard Unified Robot Description Format (URDF) files provide only low-level kinematics without the formal semantic context needed for reasoning. We present URDF2Ontology, an automated, taxonomy-agnostic neurosymbolic framework that transforms raw URDF files into populated, grounded OWL ontologies. It leverages a Large Language Model (LLM) for targeted semantic reasoning, coupled with an iterative sequential graph-purging mechanism to prevent context window saturation. To process complex kinematic structures, it employs a morphology-aware dual-track architecture featuring a bottom-up Tree Track for branching assemblies and a top-down Chain Track for serial limbs. Guided by neurosymbolic guardrails, the framework extracts functional sub-graphs and asserts populated ontologies aligned with arbitrary user-provided taxonomies. Empirical evaluation across a diverse fleet of heterogeneous robots demonstrates strong schema alignment, valid structural extraction, and a significant reduction in manual domain authoring overhead.
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URL
https://arxiv.org/abs/2611.13850
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Satellite Pretraining Is Not One Thing: A Matched-Pair Study of Generic and Earth-Observation Foundation Models for Scene Classification
2026-11-10 10:10:29Sandarbh Agrawal, Rakshith Sathish, Ashwathi NambiarAbstract
Geospatial foundation models are pretrained on satellite and aerial imagery, but whether such an encoder beats a strong generic one for few-label land-use/land-cover mapping remains unclear, as prior comparisons rarely isolate the pretraining data. We study five matched pairs of Earth-observation (EO) and generic encoders sharing objective and architecture (DINO/SatDINO, DINOv3/DINOv3-SAT, MAE/SatMAE, MAE/Scale-MAE, CLIP/RemoteCLIP) within a benchmark of 14 frozen encoders on five RGB scene-classification datasets (0.06-30 m GSD). With native preprocessing, we evaluate k-NN, linear and attentive probes and image retrieval over six low-label splits, using paired per-image significance tests. EO pretraining is not uniformly helpful: on most datasets and metrics, it significantly improves three pairs (SatDINO, Scale-MAE, RemoteCLIP, the latter evaluated only on unseen datasets) and significantly hurts two (linear probe: DINOv3-SAT by up to 22.5 points, SatMAE by up to 8.8), with opposite outcomes even for two MAEs pretrained on the same fMoW-RGB imagery. These effects are robust to patch-token pooling and attentive probing, concentrate on small man-made objects, and are largest with 1-5% labels. Across encoders, the silhouette score of frozen embeddings predicts k-NN accuracy and retrieval mAP almost perfectly (Spearman $\rho \geq 0.96$ on four of five datasets). Pretraining on satellite imagery is thus not a reliable selection criterion; candidate checkpoints must be validated on target data.
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URL
https://arxiv.org/abs/2611.13849
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PolyRoute: A Twelve-Language and Code-Mixed Benchmark for Typed-Decision Routing, with Baselines and a Leaderboard
Abstract
Typed-decision encoders answer a question about a text in one forward pass, but their behaviour outside English is rarely measured on a fixed yardstick. We release PolyRoute: 322 native-language support messages in 12 languages and 9 writing systems, 156 code-mixed or romanised messages (Hinglish, Spanglish, Arabizi), 967 optional native training rows, and a protocol for a three-way department-routing decision. Labels come from Qwen3.8-27B with a blind second pass (91% of candidates kept); an independent model, gemma4-31b, agrees on 97.2% of test items, and the largest character 5-gram similarity between any test text and any training text is 0.33. A leaderboard of 13 systems gives 61.2% for the English-root checkpoint, 77.3% for the shipped multilingual one and 96.6% for the best fine-tune; TF-IDF with logistic regression reaches 91.9%. On four withheld languages the three multilingual systems score 77%, 90% and 93%. On code-mixed text the English root (85%) is nominally ahead of the shipped multilingual checkpoint (79%; p=0.134). The split resolves differences only above about 4 points. All texts and labels are LLM-generated.
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URL
https://arxiv.org/abs/2611.13843
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STABLE: A Continual Learning Optimizer with Adaptive Drift Control
2026-11-10 10:00:14Xiaoyan Li, Lanpei Li, Massimo Coppola, Vincenzo Lomonaco, Antonio CartaAbstract
Continual learning suffers from catastrophic forgetting, leading to the loss of past knowledge and unstable adaptation across task streams. Existing approaches typically address this issue through replay buffers, architectural changes, or additional regularization terms. We argue that forgetting is a consequence of unstable learning dynamics, which may benefit from an optimizer-level solution. The main challenge is that learning dynamics are time-dependent, as demonstrated by empirical phenomena such as the stability gap. First, we formally prove that, for distance-based classifiers, bounded parameter drift guarantees bounded margin erosion under a local score-stability condition. Based on this insight, we propose STABLE, a primal-dual optimizer with adaptive drift control. STABLE enforces a drift budget by increasing the dual variable when the budget is violated and decreasing it otherwise. This results in high stability without penalizing plasticity. Experiments on long-horizon unimodal streams and CLIP-based multimodal streams show that vanilla PEFT baselines trained with STABLE match or outperform specialized continual learning methods. In the multimodal setting, STABLE further preserves zero-shot transfer, matching or exceeding dedicated multimodal continual learning methods. Code is available at this https URL.
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URL
https://arxiv.org/abs/2611.10655
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MusicFlux: Flexible Conditioning for Text-Guided Music Generation and Editing
2026-11-10 10:00:03Teysir Baoueb (IP Paris, LTCI, IDS, S2A), Leonardo Boulitreau de Menezes Martins Marques (IP Paris, LTCI, IDS, S2A), Paraskevas Stamatiadis (S2A, LTCI, IDS), Ga{\"e}l Richard (S2A, IDS, IP Paris, LTCI)Abstract
Music editing transforms existing recordings while preserving their original attributes. Recent approaches adapt pretrained text-to-music models for tasks like inpainting, event insertion, or restoration by conditioning them with context audio. It was recently proposed for image editing to unify generation and editing by treating the source image as in-context information. However, applying this directly to music is computationally expensive due to long audio sequences. In this work, we develop MusicFlux, a text-guided music editor built on an efficient pretrained flow-matching text-to-audio model. We introduce two conditioning approaches that trade off editing performance and computational efficiency. Experiments show that both are competitive with strong baselines, with one achieving better editing quality and the other preserving the original sequence length and substantially improving computational efficiency.
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URL
https://arxiv.org/abs/2611.13834
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Ceci n'est pas une pipe -- Toward a Symbolic Solver for the Abstraction and Reasoning Corpus Using Evolutionary Computation
2026-11-10 09:57:01Luca Favole, Giorgio Mongardi, Giovanni Squillero, Alberto TondaAbstract
The Abstraction and Reasoning Corpus (ARC) is a benchmark designed to assess the capability of Artificial Intelligence (AI) systems to generalize starting from a few samples, a task humans excel at. The ARC-AGI contests held since 2020 have been the focus of intense competition, with participants proposing approaches ranging from traditional symbolic AI to Transformer architectures. Despite a long history of successes, evolutionary algorithms (EAs) were notably absent from the approaches appearing in the main contest. As score-and-search program synthesis approaches, EAs suffer from issues related to choosing the proper representation in the Domain-Specific Language applied to the problem (for example, pixel-level or object-level), and distinguishing between two candidate solutions producing the same outputs. In this work, we present the first fully symbolic, evolutionary-based program synthesis approach submitted to the ARC-AGI-2 main contest. The main contributions are: evolving the grid parser and the output projector together with the program that transforms the grid, so that a task-specific language emerges during program synthesis; grounding the symbols the parser can extract in core knowledge theory from cognitive psychology; and an object-aware fitness that grades partially correct outputs beyond pixel-level discrepancies.
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URL
https://arxiv.org/abs/2611.13831
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CASCADE: Constraint-Aware SCAffolded DEcomposition for Logical Anomaly Detection
2026-11-10 09:46:23Jinchan Kim, Jinhee Im, Hyunsouk ChoAbstract
Logical Anomaly Detection (LAD) requires verifying whether all category-specific constraints, such as object counts, pairing relations, and measurement ranges, are satisfied by a query image given only a few normal references. Recent LAD methods based on Large Vision-Language Models (LVLMs) formulate this as checklist verification, decomposing the decision into independent textual checks. This decomposition, however, is text-only. Every item still reads the same unmodified query image, so the LVLM must extract different forms of visual evidence from one raw image. We identify this text-image mismatch as a constraint-specific perception gap, the source of two failure modes: instance conflation for binding constraints and scale drift for calibration constraints. To diagnose whether these failures stem from insufficient reasoning or insufficient perception, we compare textual reasoning guides and visual perception guides in a training-free setting. Our analysis shows that reasoning over the same image provides little benefit, whereas adapting the visual input to each constraint substantially improves verification accuracy. Based on this finding, we propose CASCADE, a training-free framework that extends checklist decomposition using constraint-specific visual scaffolds. We further introduce CASCADE++, which adapts these scaffolds at the object level by deriving their configurations from the constraint structure and reference distribution. Across MVTec-LOCO and VID-AD, CASCADE++ surpasses the full-shot state of the art by 3.9 AUROC points with only three references, and improves over the strongest VID-AD baseline by 11.4, transferring across multiple LVLM backbones without any training.
Abstract (translated)
URL
https://arxiv.org/abs/2611.13820
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Swanada: Split-Encoder Capability-Routed Conformer CTC and Sub-30 MB On-Device Speech Recognition Across Twelve Scripts
2026-11-10 09:43:36Hemanth HMAbstract
Client-side automatic speech recognition (ASR) across Indic and Classical scripts eliminates cloud transcription costs, network tail latency, and server-side audio retention, yet neural exports face four systems bottlenecks in browsers and mobile runtimes: (1) monolithic per-language Conformer checkpoints require ~177 MiB per script (> 2.1 GiB across 12 scripts), exhausting CacheStorage quotas; (2) static relative positional encoding tables embed 10.2-20.5 MB of FP32 constants while 1x1 Conv1d layers trigger slow or unsupported ConvInteger kernels in WebAssembly SIMD; (3) sliding-window CTC flickers on boundary tokens; and (4) mobile WebAudio pipelines suffer 44.1/48 kHz sample-rate mismatches and silent AudioWorklet stalls under iOS WKWebView. We present Swanada, an open-source 16 kHz streaming ASR system spanning Classical Sanskrit, Indian English, and ten Indian languages (sa, en, hi, kn, mr, bn, ta, te, ml, gu, pa, or) across browser WebAssembly, this http URL, and Python. Swanada pairs capability-routed shared INT8 Conformer encoders (a 17-layer 177.38 MiB Studio tier at $d = 512$ for desktop/servers and a distilled 14-layer 25.35 MiB Mobile tier at $d = 256$ for phones) with twelve hot-swappable 515.0 KiB native-script linear CTC heads ($257 \times 512$), cutting 12-language storage by $11.6\times$ (183.4 MiB) and $67.8\times$ (31.39 MiB; 25.85 MiB first load). Runtime protobuf tail surgery exposes the shared representation in $< 2$ ms, while dynamic positional synthesis, MatMul pointwise convolutions, and post-quantization QInt8 head calibration preserve sub-30 MB accuracy. Across $N = 480$ held-out and $N = 1,280$ open public test clips (FLEURS, LibriSpeech, GLOBE, AMI, wild Sanskrit), Swanada achieves 5.43% held-out and 8.87% 12-language open CER on Studio (18.56% and 19.23% on Mobile) at $0.0097\times$-$0.0264\times$ RTF, with 30.6 ms median TTFT and 0.00% committed-prefix churn.
Abstract (translated)
URL
https://arxiv.org/abs/2611.13814
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Relaxing Cross-Modal Correspondence for Multimodal Remote Sensing Pretraining
2026-11-10 09:38:55Xianping Ma, Yu Zhang, Mingzhe Jiang, Wanxin Xie, Qing Zhu, Nan Xu, Xiaokang Zhang, Yuanxin YeAbstract
Multimodal remote sensing pretraining commonly relies on exact instance-level correspondence across modalities, implicitly treating strictly paired observations as a prerequisite for learning transferable representations. In this work, we revisit this assumption by relaxing cross-modal correspondence from the instance level to the semantic level. We introduce Semantic Pairing (SemPair), a pairing-relaxed pretraining strategy that replaces exact instance pairs with class-consistent cross-instance pairs. To characterize the effect of correspondence relaxation, we formulate a latent-factor model that separates cross-modal dependence into shared semantic structure and instance-specific correlation, showing that SemPair preserves the former while marginalizing instance-specific cross-modal correlations in expectation. We further introduce Mixed Pairing (MixPair) as a controlled interpolation between semantic and exact pairing to study correspondence granularity along a continuous spectrum. Extensive experiments consistently show that SemPair achieves transfer performance comparable to exact pairing (ExaPair), while MixPair reveals a non-monotonic relationship between downstream transfer and the instance-pairing ratio. These results demonstrate that exact instance correspondence is not a prerequisite for effective multimodal remote sensing pretraining and establish cross-modal correspondence granularity as an important design dimension for transferable multimodal representation learning. More broadly, this finding suggests a practical route toward scaling multimodal pretraining with reduced dependence on costly instance-aligned data.
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URL
https://arxiv.org/abs/2611.13807
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Bridging Graph and Pairwise Learning for Gene Regulatory Network Inference from scRNA-seq Data
2026-11-10 09:34:28Hang Li, Jiaxin Qi, Yan Cui, Yuhua Zheng, Jianqiang HuangAbstract
Motivation: Gene regulatory networks (GRNs) capture the underlying interactions through which transcription factors (TFs) regulate genes. Based on gene expression data, existing GRN inference approaches generally fall into two categories: graph-based methods, which model the GRN as a whole graph, and pairwise-based methods, which decompose the GRN into individual TF-target gene pairs for modeling. However, each approach exhibits limitations that are precisely the strengths of its counterpart. Graph-based methods tend to overfit due to their reliance on a single training graph, whereas pairwise-based methods benefit from abundant TF-target training pairs. In contrast, pairwise-based methods overlook the global topological structure, which is essential for comprehensively capturing regulatory mechanisms. Results: To address these limitations, we propose scGPL, an end-to-end unified framework that jointly models global regulatory topology and local interactions. scGPL extracts macro-level features from the global regulatory graph and introduces a dynamic, importance-guided subgraph sampling mechanism to capture fine-grained local dependencies. By fusing global representations with subgraph-enhanced local features, our framework bridges the gap between the two paradigms, incorporating essential whole-graph topological dependencies while retaining the data abundance advantage of pairwise methods. Extensive experiments on seven benchmark datasets demonstrate that scGPL consistently achieves state-of-the-art performance, with up to 13.7% improvement over the strongest baseline, validating the effectiveness of our integrative design. Availability and implementation: The source code is maintained on GitHub (this https URL), and the datasets and versioned releases are archived at this https URL for reproducibility.
Abstract (translated)
URL
https://arxiv.org/abs/2611.13801
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Integrating Action Prefix Prediction and Alignment Across Modalities for Multimodal Reinforcement Learning
2026-11-10 09:20:04Sijie Xu, Francisco CruzAbstract
Learning representations from multimodal observations is difficult in reinforcement learning with limited interaction data. Multimodal Joint Predictive Representation combines multimodal latent prediction with contrastive learning across modalities, but its recursive rollout depends on earlier predictions and its pairwise alignment focuses on correspondence between modalities. We propose Improved Predictive Representation, which combines prediction from action prefixes with alignment at the observed anchor based on Contrastive Multimodal learning. At each horizon, it predicts future representations directly from the observed anchor and the corresponding sequence of actions. We evaluate two crop configurations: IPR-S with a minimum retained crop area of 10%, and IPR-H with 50%. Across five DeepMind Control Suite tasks, IPR-H achieves an average return across tasks that is 10.0% higher than the baseline with visual and depth images and 3.4% higher with visual images and position vectors. The relative performance of the two configurations varies across tasks. In Webots, both IPR configurations achieve higher mean final returns than the baseline without LiDAR, but not when LiDAR is available.
Abstract (translated)
URL
https://arxiv.org/abs/2611.13782
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Softness is something you also need! Why compliance helps control: information metrics of a passive walker with compliant ankle
2026-11-10 09:17:17Fabio Bonsignorio, Elisabetta Barletta, Sorin Dragomir, Francesco Esposito, Enrica ZereikAbstract
A great gap in adaptivity, flexibility, and dexterity still exists between intelligent robots, whether they are made of rigid or (partially) compliant components, and their naturally evolved animal and vegetal counterparts. One reason could be of `paradigm' nature. On the one hand, most robots (both rigid and soft) are still designed by following a `Cartesian' approach, with top-down control and a clear mind-body separation. Designing artificial agents on the basis of the principles that we observe in biology is not an easy task. The principles of organization of animals and plants rely on morphological computation and emergence of fit behaviors from loosely coupled networks of embodied agents. Modeling and control require radically new approaches. In this paper we briefly recall and explain some seminal mathematical results linking information metrics and dynamics of the agents, already published years ago; we integrate them with some recent methods developed by us and by the community, we highlight some brief remarks about their relevance and we hint to our current and near future work towards finding concrete and efficient ways for the modeling and control of completely or partially compliant artificial agents and for a better understanding of physical intelligence in nature. We present a technical note summarizing phase-space volume calculations for inverted-pendulum and passive-dynamic walking models, following our proposed framework. Starting from the McGeer compass gait, we introduce knee-ankle compliance, foot-rocker effects, and a Ruina-style compass gait with distributed leg inertia. Standard heel-strike maps are derived and used in the estimation of viable phase-space volumes $W(\gamma)$, based on a state-dependent Monte-Carlo and Reproducing Kernel Hilbert Spaces methods. We show how the methods based on RKHS allow deeper and more subtle analysis.
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URL
https://arxiv.org/abs/2611.13779
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DisasterAgent: An Evidence-Driven Agent for Verifiable Disaster Report Generation From Remote Sensing Imagery
2026-11-10 09:15:06Zhijian Li, Jiawei Song, Chao Ren, Yidan Zhang, Peijin Wang, Xian Sun, Kun FuAbstract
Remote sensing disaster assessment is moving from simple damage classification toward comprehensive report-level analysis. In this setting, responders need not only damage descriptions but also verifiable evidence to guide response and recovery. Recent vision-language models (VLMs) and tool-augmented agents offer strong multimodal reasoning and perception, but they struggle to provide the evidence required for high-stakes verification. To address these limitations, we propose DisasterAgent, an evidence-driven agent that uses a Perception-Augmentation-Generation workflow to generate verifiable disaster reports from bitemporal optical imagery. DisasterAgent first invokes a specialized vision expert toolkit in the perception phase to build a Spatiotemporal Perception Graph (STPG), serving as a structured memory to store and organize disaster-induced changes across space and time. Evidence-based Augmentation (EA) then extracts evidence from the STPG, attaching inline citations that form a closed evidence loop from each statement to the supporting visual evidence. Extensive experiments on the DisasterM3 and RSCC benchmarks demonstrate that DisasterAgent consistently outperforms general-domain VLMs, remote sensing-specialized models, and existing remote sensing agents. Notably, compared with the original model, it improves the average score for disaster report generation on DisasterM3 by 13.5\% and ST5-SCS on RSCC by 15.34\%, providing a more accurate and verifiable solution for disaster emergency response. The code will be available at this https URL.
Abstract (translated)
URL
https://arxiv.org/abs/2611.13776
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MSCR: Jointly Balancing Utilization Across Modalities and Discovering Synergistic Information
2026-11-10 09:06:09Xinyu Chen, Liangjian Wen, Jiang Duan, Dongkai Wang, Yong Dai, Jiayu Bai, Jianzhuang Liu, Zhen Tian, Guoping Qiu, Zhao KanAbstract
In multimodal learning, modality imbalance often lets one modality dominate optimization and keeps the model from fully exploiting cross-modal interactions. Balance-oriented methods such as the Multimodal Competition Regularizer (MCR) perform well by alleviating this imbalance during training. These dynamic balancing methods, however, mainly adjust modality contributions and do not consider how imbalance affects the formation of synergistic information during fusion. Synergy is a major source of multimodal advantage, because it is predictive gain that cannot be recovered from unimodal evidence alone. We propose the Multimodal Synergistic Competition Regularizer (MSCR), a fusion method that jointly promotes balanced modality utilization and the discovery of synergistic information. MSCR has two complementary objectives. An anti-dominance objective suppresses excessive unimodal influence and leaves room for synergistic information, and a synergy objective encourages the fused predictor to outperform a non-synergistic unimodal reference. An adaptive gate further concentrates the regularization on samples that need stronger collaborative modeling. Experiments on five benchmarks show that MSCR consistently improves performance over MCR and strengthens synergistic capability. It raises conditional recovery, the accuracy of the fused prediction on samples that the unimodal predictors misclassify, as well as the share of the model's output that InterSHAP attributes to cross-modal interactions. Its gain in conditional recovery persists when the fusion module is Transformer-based. Code is available at this https URL.
Abstract (translated)
URL
https://arxiv.org/abs/2610.24395
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MAGAR: Multimodal Agents for GUI-Based 3D Mechanical Assembly and Minimal Rework
2026-11-10 09:01:56Jingxuan Wei, Jiahao Fu, Fuqiang Wang, Xiaoming Wu, Yuwen Liu, Kaiwen Wei, Ming Yang, Junnan ZhuAbstract
A GUI command can be correct at the interface level yet still produce an incorrect assembly. An agent must identify the relevant components, respect their structural relationships, and determine which parts should move during recovery. We introduce MAGAR-Bench, a benchmark of 4,000 multimodal samples from 26 assembly families that separates Assembly Decision, Atomic Action, and Minimal Rework. For rework, the objective counts distinct moved parts within the validated recovery candidate set for each state, rather than the number of actions. We also introduce MAGAR, a selective correction framework built on a frozen policy obtained by supervised fine-tuning. Its key design matches correction granularity to output dependencies. Structured candidates revise assembly fields and rework scope, while complete action candidates keep native GUI primitives coupled with their parameters. A learned selector retains the original prediction unless a candidate passes a task-specific intervention threshold. On recorded states from held-out assembly families, MAGAR improves Overall, the task-balanced aggregate, from 37.50 to 41.39, with gains on all three tasks. Across 209 interventions, 70 correct an error and 22 introduce one. These results support task-specific correction while highlighting the remaining tradeoff between fixing errors and preserving reliable predictions.
Abstract (translated)
URL
https://arxiv.org/abs/2611.02472
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Mixed Signals: Weight-Space Programming for EEG and ECG
2026-11-10 08:59:09Dara Varam, Taraneh Aminosharieh Najafi, David AtienzaAbstract
Weight-space programming allows language models to read a trained neural network's weights and edit them. This opens the door to ``training'' by reasoning rather than through gradient descent. Prior work has demonstrated its functionality and promise for game-playing networks and fixing specific failures in language models, even extending to diffusion models. In this work, we present its applicability to models trained on biosignal data, specifically EEG and ECG data. We show that frontier models are not only able to debug specific faults planted in biosignal-based models without being told what these faults are, but are even capable of writing all the weights of a network from scratch, given only the architecture, the task, and a minimal set of training subjects. In particular, in one set of experiments, a language model was able to match standard gradient-descent training using $6\times$ fewer training subjects, through reasoning alone and without any gradient descent step. Networks written by Claude Opus 5.5 also scored higher than classic hand-crafted EEG pipelines (alpha band power, and common spatial patterns with linear discriminant analysis) when built from the same 5 subjects. We also highlight some of the limitations, which include the inability of language models to improve already well-trained classification models, and their incapacity to reliably recognize, from the weights alone, the task a network was trained on. Overall, our results indicate that weight-space programming can be useful for small networks, such as those deployed on edge devices and wearables, but the concept still requires further investigation before it can be used in practice.
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URL
https://arxiv.org/abs/2611.13758
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Bridging the Evidence-to-Execution Gap:A Reflective Agent for Multi-Objective Peptide Design
2026-11-10 08:57:01Haosen Zhang, Yang YangAbstract
Large language models can reason over scientific literature, but textual plans do not reliably produce biological sequences with the intended properties. Sequence generators capture sequence patterns, yet they do not interpret evidence, choose interventions, or reflect on outcomes. This separation creates an evidence-to-execution gap between scientific reasoning and sequence-level control. We introduce EASER, a reflective agent that connects the two through a learned property interface. The interface consists of property-specific low-rank directions trained offline and fixed during search; an LLM controller (the controller) composes them to steer a frozen diffusion generator. From retrieved evidence, sequence context, and prior outcomes, it proposes intervention hypotheses that specify anchors, editable positions, and coefficients. Probe-and-Steer tests these hypotheses and allocates further samples from their joint predicted responses; reflection updates the agent's memory. On computational antimicrobial peptide design, EASER balances activity, non-hemolysis, and non-toxicity. Explicit hypothesis formulation yields larger multi-objective gains than direct action generation, and ablations support evidence retrieval, episodic history, reflection, and Probe-and-Steer. EASER achieves the highest mean hypervolume and lowest mean IGD+ among the evaluated search policies and generators on screened candidates. These results show that a learned property interface can make literature-grounded reasoning executable at the sequence level.
Abstract (translated)
URL
https://arxiv.org/abs/2610.06190
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A Hardware-Trained Generative Quantum Eigensolver for Sample-Based Quantum Diagonalization of Organotin Hydroxides up to 70 Qubits
2026-11-10 08:54:35Kunal Kumar, Kimberlee Keithley, Toshiya Iwamori, Shu Kanno, Ikko Hamamura, Takao Kobayashi, Akira Koseki, Qi Gao, Naoki Yamamoto, Hiroshi Horii, Yuri Kobayashi, Borja Peropadre, Kouhei Nakaji, Toru Imai, Takayuki OsogamiAbstract
Quantum hardware can provide feedback for training circuit generators beyond the reach of exact classical simulation. We train generative quantum eigensolver (GQE) policies, transformers conditioned on molecular descriptors, to generate the state-preparation circuits for sample-based quantum diagonalization (SQD). Training runs first on a noiseless simulator and then with the IBM Heron processor ibm_kobe inside the loop, at 46 and 70 qubits ($1.2 \times 10^8$ shots for the four main training runs). A classical CCSD(T) reference energy of the training molecules enters only an admission gate and two auxiliary reward terms. During hardware training, a reward penalty prevents collapse to circuits that sample only the Hartree-Fock determinant. Policies trained on transition-metal complexes are applied without retraining to Sn(OH)$_3$-Me and its hydrates, minimal models of organotin photoresists for extreme-ultraviolet lithography, from 32 to 70 qubits. After one round of hardware sampling, followed by classical ranking and recovery of the cached counts with the molecular Hamiltonian and no further QPU calls, 27 of 28 runs at 46-70 qubits are within 15 mHa of the density-matrix renormalization group (DMRG) reference (median 4.5 mHa), and in all eight runs with an untrained control the trained policy is more accurate. At 56-70 qubits the selected circuits use 34-72 times fewer two-qubit gates than the local unitary cluster Jastrow (LUCJ) circuit transpiled for the same device. These results demonstrate that circuit generators can be trained with quantum hardware at 70 qubits.
Abstract (translated)
URL
https://arxiv.org/abs/2611.13755
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