Objective: To improve the spatial and temporal resolution of aortic 4D flow MRI through a unified deep learning framework for post-acquisition super-resolution (SR) of reconstructed velocity vector fields. Methods: We propose CURRENT, a recurrent neural network that performs spatial and temporal SR with a single network architecture. Supervised training was conducted using paired low- and high-resolution datasets generated by embedding computational fluid dynamics simulations of aortic flow into in vivo thoracic MRI backgrounds, followed by controlled spatial and temporal downsampling. CURRENT was evaluated for two-fold spatial and temporal SR against 4DFlowNet and for two-fold spatiotemporal SR against sequential spatial and temporal SR pipelines based on 4DFlowNet. Image-based and k-space-based quantitative metrics were considered and conventional interpolation were used as baselines. In addition, the impact of CURRENT's spatiotemporal SR on physics-informed relative pressure estimation was assessed. Finally, the ability of CURRENT to generalize from synthetic training data to in vivo acquisitions was investigated. Results: CURRENT achieved superior spatial SR performance and comparable temporal SR performance to dedicated 4DFlowNet models while providing a unified solution for both tasks. Simultaneous spatiotemporal SR using CURRENT yielded more accurate relative pressure estimates than either spatial or temporal SR alone and outperformed sequential 4DFlowNet-based spatial and temporal SR approaches. Furthermore, the proposed model demonstrated promising generalization to in vivo 4D flow MRI data despite being trained exclusively on synthetic datasets. Conclusion: CURRENT provides a unified framework for spatial and temporal SR of 4D flow MRI. The proposed approach has the potential to enhance physics-based analysis and broaden the applicability of accelerated 4D flow MRI.
https://arxiv.org/abs/2611.14058
Although remote sensing image arbitrary-scale super-resolution (RSI-ASSR) methods support reconstruction at arbitrary or continuous scales, they predominantly condition on the relative scale factor and have not sufficiently investigated the absolute spatial resolution itself as a reconstruction prior, thereby disregarding the inherent spatial context of objects, which frequently leads to spatial-related distortions and compromised performance in downstream remote sensing applications. To address these challenges, we introduce SpatialSR, a SRe-centric arbitrary-scale RSISR method that leverages the spatial resolution (SRe) of remote sensing images (RSI) as an essential prior for super-resolution reconstruction. Distinct from existing SR methods, SpatialSR aims to restore high-resolution remote sensing images with a target SRe (typically set to 0.1m/pixel to align with the metadata of commonly used downstream task datasets). Specifically, we design a Spatial Resolution Estimation Module (SREM) to estimate the SRe of low-resolution (LR) images, thereby dynamically determining the required arbitrary scaling factor. Next, we employ a pretrained SRe-to-image diffusion model to extract SRe-specified texture-style codes, which are further incorporated into a carefully designed Resolution-aware Style Consistency Module (RSCM) to constrain the SRe-aware texture consistency of reconstructed images. Furthermore, to overcome the high computational expense inherent in diffusion-based SR methods, we wrap the iterative diffusion process as a Trajectory Consistency (TC) loss, which enables comparable reconstructed texture quality of the generative model in SpatialSR within a single step. Extensive experiments demonstrate that the proposed SpatialSR achieves state-of-the-art (SOTA) performance on commonly used RSISR and downstream (image classification and segmentation tasks) datasets.
https://arxiv.org/abs/2611.13046
Plug-and-play (PnP) methods reconstruct images by alternating a data-fitting step with an image denoiser. Their performance depends on two parameters: the step size $\gamma$ and the measurement noise level $\sigma$. In practice, $\gamma$ is often tuned by grid search over validation images and must be retuned whenever the problem setting changes, and $\sigma$ is assumed known or estimated separately. We propose AdaptivePnP, a PnP framework that jointly estimates $\sigma$ and $\gamma$ at every iteration from the data-fitting residual. To do so, we apply the PnP virtual model to the data-fitting proximal map and show that the residual is zero-mean Gaussian with covariance parameterized by $\gamma$ and $\sigma$. However, when one parameter is much larger than the other, the residual carries little information about the smaller one and using the maximum likelihood (ML) estimator can degrade the PnP iterations. We therefore introduce the identifiable maximum likelihood (IML) estimator, which restricts the ML estimator to an identifiable window in which the normalized Cramér--Rao bound of every parameter is bounded by a user-specified tolerance. For the virtual model, this window is an interval of ratios $\rho = \gamma/\sigma$, so computing the IML estimate reduces to a one-dimensional search over $\rho$. We apply AdaptivePnP to two standard PnP methods, yielding algorithms that require neither a tuned $\gamma$ nor a known $\sigma$. On image deblurring and super-resolution, AdaptivePnP matches or outperforms PnP baselines tuned with the true $\sigma$. Code is available at this https URL.
https://arxiv.org/abs/2611.09845
Existing continuous space-time video super-resolution methods often infer motion from only two endpoint frames and model the two motion directions independently, making them vulnerable to ambiguous correspondence and inconsistent trajectories. We introduce a continuous STVSR framework that combines long-context encoding, continuous HR feature lifting, and an endpoint-anchored PixelSpline. Long-range observations provide more reliable endpoint representations, while continuous upsampling constructs detailed appearance features directly on the requested HR grid. PixelSpline explicitly models each pixel's motion as a single continuous trajectory shared by both endpoints. Using this trajectory, our method warps endpoint colors into a coarse intermediate frame and aligns the HR features for residual reconstruction. Experiments across spatial and temporal upsampling settings demonstrate that the proposed framework offers a favorable quality--efficiency trade-off.
https://arxiv.org/abs/2611.06870
Deep learning-based super-resolution (SR) can reconstruct fine-scale Earth-observation fields from coarse observations, but reconstruction accuracy alone does not provide a calibrated rule for identifying reliable spatial regions. Conformal Mask Calibration (CMC), built on conformal risk control, converts a spatial uncertainty score into a trust mask and controls the expected worst-case local distortion under exchangeability. However, its fixed threshold can become miscalibrated in Earth-observation streams affected by seasonality and episodic events. We propose $\textit{CARM}$ (Conformal Adaptive Risk Masking), a statistical framework for adaptive spatial risk control under temporal distribution shift. CARM maintains experts with heterogeneous update rates and aggregates their threshold proposals online using an asymmetric surrogate loss, balancing rapid adaptation to distribution changes against stability during relatively stationary periods. All updates are causal and use only mature feedback available after a fixed delay, allowing CARM to operate with any SR model that provides a spatial uncertainty score. We prove that the time-averaged mask-conditioned risk converges to at most $\alpha$ at an $O(1/T)$ rate, without distributional assumptions and for any choice of aggregation weights across experts. On a daily South China Sea chlorophyll-$\textit{a}$ SR stream, CARM reduces the empirical violation rate from $43.49\%$ to $9.38\%$ and the moving-average exceedance frequency from $47.29\%$ to $1.22\%$ at $\alpha=0.10$, while retaining a non-trivial trusted region. Experiments on ERA5 wind and OSTIA sea-surface temperature further show consistent relative improvements across multiple SR backbones.
https://arxiv.org/abs/2611.06151
Recent pansharpening models achieve strong fusion performance on trained sensors, yet often generalize poorly to unseen sensors. Existing cross-sensor adaptation is limited by target-sensor retraining, which requires target-sensor training pairs and a dedicated training stage, and by per-image zero-shot adaptation, which is computationally expensive due to whole-network optimization for each test image. To address these problems, we propose ReTailor, a real-time sequential cross-sensor adaptation framework. Only a lightweight residual Feature Tailor is rapidly optimized under self-supervised, physics-aware constraints to correct cross-sensor shifts without modifying the well-learned fusion prior. For efficient and effective deployment, ReTailor combines content-aware patch selection, which identifies a few informative patches per image for optimization at negligible cost to improve both quality and efficiency, with rolling residual bootstrap, which inherits sensor-related knowledge across the image stream to further improve quality. Extensive experiments on cross-sensor adaptation settings show that ReTailor mitigates cross-sensor degradation both effectively and efficiently. Moreover, we compare ReTailor with Low-Rank Adaptation (LoRA), a widely used method for fine-tuning, to demonstrate the advantages of our approach. We further evaluate the core principle of ReTailor on two additional remote sensing tasks: super-resolution pansharpening and image segmentation, where it consistently improves performance. In general, ReTailor provides a highly effective and efficient strategy for deploying pansharpening models under real-world cross-sensor degradation, while also offering useful insights into managing cross-sensor degradation in other remote sensing tasks. Code will be released at this https URL .
https://arxiv.org/abs/2611.05811
High-resolution 3D indoor scene generation is crucial for immersive applications such as virtual reality, spatial computing, and robotics simulation. We introduce VoxLution, a coarse-to-fine transformer-based approach that generates high-fidelity indoor scenes with rich details, overcoming the overly smooth geometry typical of existing generative models. First, we generate a low-resolution spatial layout; then, based on this structural information, we progressively refine the scene geometry locally in chunks. Key to our approach is formulating 3D super-resolution as a sequence modeling problem over multi-resolution sparse voxel grids. To achieve this, we introduce a training-free, resolution-invariant tokenization scheme that compactly encodes the geometric information of eight octants into a single decimal number. We formulate the transformer sequence to include multiple resolutions, allowing the coarse layout to guide the generation of fine local details. To ensure coherence across local chunks, we incorporate adjacent chunk boundary information directly into the transformer sequencing. VoxLution achieves scene generation at a finer voxel resolution than existing baselines, demonstrating state-of-the-art performance on standard benchmarks with 59.6% lower FPD and 51.1% lower FID on 3D-FRONT, and 70.5% lower FPD and 73.8% lower FID on Scannet++.
https://arxiv.org/abs/2610.41501
Burst super-resolution (BSR) achieves higher reconstruction fidelity than single-image super-resolution (SISR) by aggregating sub-pixel information from multiple frames. However, it requires a burst of frames captured under near-static conditions, and such frames are unavailable for single photographs or archival images. We propose Pseudo-Burst Super-Resolution (PBSR), which brings BSR-style reconstruction to the single-image input setting by synthesizing pseudo-burst frames via zero-shot novel view synthesis (NVS). PBSR first generates pseudo-burst frames with realistic parallax using a viewpoint sampling strategy calibrated to the pixel-shift distribution of real burst datasets. The frames are then processed by a BSR backbone equipped with a geometry-aware alignment module that reuses the NVS camera parameters and estimated depth. While the NVS stage is zero-shot, the backbone is fine-tuned with an artifact-aware adaptation so that it can exploit the synthesized frames despite their generative artifacts. Experiments on the BurstSR dataset show that PBSR consistently improves in PSNR, SSIM, and LPIPS over the single-frame baseline with the same reconstruction backbone.
https://arxiv.org/abs/2610.41258
In real-world surveillance settings, facial captures from closed-circuit television systems suffer from degradations such as low resolution, motion blur, noise, and occlusions, which undermine dependable face recognition. In this study, we propose a framework for super-resolution and identity recognition, aimed at surveillance applications. For this purpose, we present the CVBL-CCTV-Face Dataset which is a dataset of real-world images taken in an unpaired manner where each pair consists of a low-quality (LQ) image of a face captured by a 8MP IP Dome CCTV camera together with a high-quality (HQ) reference image that is taken in controlled settings. In order to cope with the various problems posed by such datasets, we construct a modular system that involves face detection, deep learning-based super-resolution of low-quality face images, and identity recognition through L2-normalized embeddings extracted by an embedding model. Enhancement models are trained and tested according to three different setups, and the system is deployed for identity verification in a real-time unconstrained environment.
https://arxiv.org/abs/2610.36781
Diffusion-based real-world image super-resolution suffers from limited reconstruction fidelity due to information loss in VAE-based latent representations. Recently, pixel-space diffusion models offer a promising high-faithfulness alternative by avoiding latent compression, but adapting them to Real-ISR remains challenging due to inherent patch boundary artifacts and degraded generative capability. To address the issues and maximize the potential of pretrained pixel-space diffusion models, we propose HiFiPix, a pixel-space Real-ISR framework capable of ultra high-fidelity reconstruction and fine-grained visual generation effects. To suppress patch boundary artifacts, we penalize unrealistic high-frequency periodic components with a Cross-Scale Wavelet Discriminator (CWSD) for image-level supervision, and Mixup Contrastive Self-Distillation (MixCSD) for intermediate representation regularization. Furthermore, we uncover a heterogeneous generation-fidelity trade-off across low-rank adapters (LoRA) and propose Selective LoRA Pruning (LoRA-SP) to adaptively prune LoRA layers, enhancing generative capability with minimal deterioration of reconstruction fidelity. Extensive experiments demonstrate that HiFiPix consistently outperforms existing state-of-the-art latent space methods in terms of both restoration accuracy and perceptual quality by a large margin. Code and models will be released.
https://arxiv.org/abs/2610.35515
We evaluated synthetic pretraining and multi-cohort transfer learning for deep learning-based super-resolution of intracranial 4D Flow MRI across heterogeneous neurologic cohorts. This mixed prospective-retrospective study analyzed 18 participants (12 healthy participants, 3 with moyamoya disease, and 3 with multiple sclerosis) with paired 1.2-mm and 0.6-mm 4D Flow MRI scans. A convolutional neural network pretrained on synthetic cerebrovascular data was fine-tuned using cohort-specific or pooled multi-cohort in vivo data. High-resolution-derived inputs enabled voxel-wise evaluation; native standard-resolution scans were used for angiographic and hemodynamic analyses. Synthetic pretraining reduced mean artery-wise velocity-normalized root mean square error (vNRMSE) versus interpolation (0.147 vs 0.166). Pooled transfer learning yielded the lowest mean vNRMSE (0.119 vs 0.127 for cohort-specific models and 0.147 for synthetic pretraining), with narrower 95% limits-of-agreement widths than synthetic pretraining across all test cases (0.109-0.222 vs 0.154-0.278 m/s). Super-resolved phase-contrast angiography achieved higher precision-recall area under the curve than native standard-resolution imaging in all cohorts (0.848-0.896 vs 0.486-0.805). These results indicate that pooled transfer learning improves cross-cohort reconstruction agreement and that super-resolution can improve vessel depiction, supporting further multi-center validation for cerebrovascular imaging.
https://arxiv.org/abs/2610.35396
Tensor recovery spans heterogeneous data structures and observation processes, calling for a representation that can adapt across modalities and tasks. We propose DiffTR, an unsupervised framework that unifies tensor completion, denoising, and hyperspectral super-resolution through coordinate-conditioned diffusion. Shared factors indexed by tensor coordinates condition a compact score network, and score matching jointly learns the factors and an implicit tensor representation from the available observations. Scalar and vector-valued outputs accommodate individual entries and entire tubes, enabling a common formulation for tabular tensors, images, and videos. The framework separates representation learning from task-specific observation modeling: reverse diffusion recovers missing values; estimation via Tweedie's formula, soft thresholding, and optional spatial consistency support mixed-noise denoising; and measurement-guided sampling transfers a prior learned from low-resolution hyperspectral observations to high-resolution reconstruction, followed by post-sampling refinement with data consistency and spectral subspace regularization. This separation makes the representation compatible with different corruption models and permits task-specific constraints to be incorporated within the same recovery framework. Experiments across multiple tensor modalities and recovery tasks demonstrate competitive reconstruction quality and the flexibility of a unified conditional generative representation. The code is available at this https URL
https://arxiv.org/abs/2610.35368
Generative AI offers new approaches to turbulence problems in which incomplete observations or unresolved d.o.f. admit multiple physically plausible solutions. Potential applications include stochastic closures, super-resolution, data assimilation, uncertainty quantification, and the generation of Eulerian and Lagrangian flow ensembles. However, turbulence is not a conventional image-generation problem. Its multiscale dynamics, intermittency, extreme events, rough velocity fields and intrinsically stochastic transport make visual realism, pointwise error, and low-order spectral agreement insufficient measures of physical fidelity. We examine where generative AI provide novel capabilities with emphasis on diffusion models, score-based methods, and related probability-transport formulations. We discuss their use in unconditional generation, probabilistic reconstruction, reduced-order modeling, temporal evolution, and mesh-free representations. We argue that validation must address turbulence properties: energy transfer, structure functions, anomalous scaling, pdf tails, coherent structures, conservation laws, temporal consistency, ensemble diversity and generalization. Finally, we discuss potential limitations in validation, baseline, data availability and reproducibility, and the need for a benchmark ecosystem combining open data, standardized challenges, hidden tests, physics-aware metrics, and documented failures. This paper serves as a bridge between two communities. For AI practitioners, we provide a fair and accessible introduction to turbulence, essential for appreciating the challenges posed by the field and for assessing the physical relevance of generative models. For turbulent practitioners, we provide an introduction to the key technological aspects of Generative AI, clarifying what these tools actually do, and where their potential and current limitations lie.
https://arxiv.org/abs/2610.35123
Reconstructing 1-m imagery from Sentinel-2 combines two difficulties. The input and the reference are observed by different satellites, which differ in spatial resolution, spectral response, radiometry, acquisition time, and local geometry, so no synthetic degradation operator links them. The required magnification of ten in each spatial dimension also far exceeds the factors of two to four at which remote sensing super-resolution is usually developed. We study this real-world $\times 10$ problem using YREB-SR, which pairs 2022 Sentinel-2 RGB composites with 2022 Jilin-1 RGB references resampled to a 1-m grid over the Yangtze River Economic Belt. The benchmark contains 11,559 geographically matched scene pairs, with 6,409, 2,135, and 3,015 assigned to training, validation, and testing, respectively. We develop CrossVAR, a visual autoregressive model that predicts the 1-m latent as a nine-scale hierarchy conditioned on the Sentinel-2 input and estimates the remaining quantization residual with a diffusion refiner run without injected noise. Complete 1600 $\times$ 1600 scenes are reconstructed in overlapping windows that start on the Sentinel-2 pixel grid, as every training patch does, and every window is decoded at the size on which the decoder was trained before the windows are blended with Gaussian weights. On all 3,015 test scenes, CrossVAR achieves 27.60 dB PSNR, 0.7725 SSIM, 0.1451 LPIPS, and 7.15 FID, the best value of each metric among the compared methods. These results establish a strong autoregressive baseline for large-scale cross-sensor reconstruction. To facilitate reproducibility, the source code and implementation are publicly available at this https URL.
https://arxiv.org/abs/2610.34742
Serial electron microscopy (EM) is essential for large-volume biological imaging and connectomics, yet its throughput remains a major bottleneck, with cubic-millimeter-scale brain imaging requiring months or years. Existing deep learning-based EM super-resolution methods are limited to small upscaling factors or rely on synthetic data, offering modest acceleration and limited practical impact. We introduce ZoomSEM, a deep learning-based super-resolution method to dramatically accelerate SEM imaging. Trained on real low- and high-resolution scanning electron microscopy (SEM) pairs, ZoomSEM enables reliable recovery of 4$\times$, 8$\times$, and up to 16$\times$ higher-resolution images from fast low-resolution scans while preserving fine neuronal structures critical for connectomic analysis, achieving up to 30-fold effective acceleration. Extensive experiments across datasets of diverse biological samples demonstrate robust generalization under realistic low-resolution acquisition. This advance enables high-resolution, large-volume serial EM imaging at unprecedented speed, poised to transform connectomics and related fields.
https://arxiv.org/abs/2610.33580
Web platforms run on multivariate time series, from service telemetry and Web traffic logs to sensor streams served through Web APIs. Yet, retention policies often archive them at coarse granularity to save storage and bandwidth. Decisions such as autoscaling, alerting, and billing operate at finer granularity than existing forecasters reach, since these models predict at the resolution of their input. We therefore introduce Multivariate Time Series Super-Resolution Forecasting (MTS-SRF), which forecasts fine-grained futures from coarse histories, and propose TimeMagnifier to address its three challenges. Fourier Anchor counters data sparsity by fitting each input window to a trend-Fourier structure with sparse cross-variable gating; De-noise Only constrains fine-grained ambiguity by refining along the resolution axis rather than the noise axis, lengthening the grid level by level; and banded DTW Alignment corrects cross-resolution misalignment against the coarse forecast. On the first MTS-SRF benchmark, with ten datasets from five domains, real archived cross-resolution pairs, strengthened baseline adaptations, and five-seed significance tests, TimeMagnifier is best on every dataset, resolution coefficient, and metric against 15 baselines and cuts MSE by 12.3% on average. Its De-noise Only and DTW stages also transfer as a plug-in that lowers the MSE of existing forecasters by 5.1% to 9.0%. Code will be made publicly available.
https://arxiv.org/abs/2610.33470
4D Flow MRI promises opportunities for non-invasive mapping of neurovascular hemodynamics, but its clinical utility faces trade-offs between resolution, acquisition time, and noise. Deep learning-based super-resolution offers a post-scan solution, but supervised approaches require paired or domain-specific data, while patient-specific physics-informed models can be computationally demanding. This creates a need for unsupervised reconstruction models that can adapt to individual acquisitions without paired high-resolution training data, while remaining robust across anatomy, disease severity, and acquisition quality. To address this, we introduce a spectrally tuned implicit neural representation (INR) framework for intracranial 4D Flow MRI, representing the velocity field as a continuous coordinate-based neural field using WIRE activation functions with tunable spectral bias. Data-driven and physics-informed variants were evaluated in nine cerebrovascular cases spanning healthy controls and moderate-to-severe intracranial atherosclerotic disease, using CFD-derived high-resolution reference fields, MR-realistic synthetic low-resolution inputs, and direct fitting to acquired in-vivo data. Cohort-optimal spectral-bias settings generalized across subjects with only small increases in relative error compared with subject-specific optima, reducing the need for case-specific hyperparameter tuning. Physics-informed regularization provided modest additional accuracy but required substantially longer optimization, whereas the data-driven INR achieved near-comparable reconstruction performance within minutes. The framework also remained robust to acquisition-realistic noise and moderate VENC-dependent aliasing. These findings establish spectrally optimized INRs as a flexible unsupervised approach for mitigating acquisition-related trade-offs in intracranial 4D Flow MRI.
https://arxiv.org/abs/2610.33124
Learnable Representations (LRs) can fit parametric families of functions to diverse kinds of signals. These emergent neural-native data formats are gathering interest in the scientific community due to their compactness, resolution-agnosticism and amenability to direct neural processing. On the other hand, gigapixel images are becoming increasingly widespread across a variety of scientific, cultural, and industrial domains. In this paper, we present GigaBench, the first benchmark and experimental evaluation focused on deploying LRs with gigapixel imagery. GigaBench includes images collected, acquired, and synthetically rendered across diverse domains, and addresses image compression and super-resolution. We adapt a representative set of LRs, spanning Implicit, Hybrid, and Explicit methods, so as to operate reliably at the gigapixel scale on consumer hardware. Through systematic evaluation across reconstruction quality, model size, compression and inference times, we identify consistent trends across methods and suggest actionable guidance for future investigation.
https://arxiv.org/abs/2610.31644
Generating 360-degree panoramas requires both local perspective fidelity and global spherical continuity. Existing representations face a trade-off: equirectangular projection (ERP) enables seamless panorama modeling but suffers from severe distortion and a domain gap to pre-trained image generators, whereas cubemaps preserve perspective geometry but often produce inconsistent faces and visible seams. We present Squaring-the-Sphere, a panoramic image generation framework built on a novel representation CubeAtlas, which unfolds all cubemap faces into a single compact canvas. By arranging orientation-aligned, rotated polar regions alongside the equatorial faces, this representation preserves the perspective geometry of cubemaps while organizing the cross-face relationships required for seamless panorama assembly. It further enables a pretrained diffusion transformer to model the complete panorama jointly in a single pass, without altering the backbone architecture or positional encoding. While CubeAtlas has a token count comparable to ERP, its structured layout makes many dense attention interactions unnecessary. We therefore introduce a layout-aware sparse attention mask that preserves the interactions required for panorama continuity while removing geometrically irrelevant token pairs. As a result, CubeAtlas achieves better quality than ERP modeling with lower attention computation. Furthermore, we introduce a training-free super-resolution technique and a fusion scheme that enhance fine details in distortion-free perspective space before achieving the final ERP panorama. Experiments on various benchmarks demonstrate that our method improves geometric fidelity, cross-view consistency, and high-resolution visual quality over previous methods.
https://arxiv.org/abs/2610.31565
Reducing MRI acquisition time improves patient comfort, reduces motion artefacts, and increases scanner throughput. Clinical protocols often shorten acquisitions by sacrificing spatial resolution, particularly along the slice axis. Super-resolution can recover higher-resolution images, but existing methods are typically specialised to one scale or acquisition geometry, limiting their use across heterogeneous clinical protocols. We present GSMR3D, a continuous volumetric model that reconstructs arbitrary isotropic and anisotropic resolutions with a single checkpoint per MRI contrast. It combines a learned dictionary of anisotropic 3D Gaussian prototypes with scale-conditioned frequency encoding and an exact measurement-consistency projection, keeping reconstructions consistent with the acquired low-resolution data. We train separate models on 3,731 contrast-enhanced T1-weighted and 30,254 T1-weighted brain MRI volumes from clinical and population-based cohorts. We evaluate GSMR3D against geometry-specific specialists for isotropic, in-plane, and through-plane super-resolution using reconstruction quality and downstream tasks: brain tumour segmentation, brain-metastasis detection, and brain parcellation. GSMR3D outperforms specialists at isotropic $2\times$ and achieves better LPIPS, DISTS, and FID across all geometries, although specialists retain higher PSNR in anisotropic settings. It more faithfully preserves glioma segmentations across all geometries, achieves the highest lesion sensitivity on an independent brain-metastasis cohort, and the highest brain-parcellation agreement for isotropic and in-plane reconstruction. Reconstruction takes about 6s per volume, adding little overhead relative to acquisition-time savings. GSMR3D offers a flexible approach to MRI scan-time reduction with one model per contrast across geometries while preserving information relevant to downstream tasks.
https://arxiv.org/abs/2610.24858